Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) bsrG-as-bsrG/-
Location 2253087..2253377 Replicon chromosome
Accession NC_018520
Organism Bacillus subtilis QB928

Toxin (Protein)


Gene name bsrG Uniprot ID L8EAY0
Locus tag B657_RS22460 Protein ID WP_009967548.1
Coordinates 2253087..2253203 (+) Length 39 a.a.

Antitoxin (RNA)


Gene name as-bsrG
Locus tag -
Coordinates 2253198..2253377 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B657_RS11690 2249014..2249184 - 171 WP_009967544.1 bacteriocin sublancin-168 -
B657_RS11695 2249481..2249798 - 318 WP_009967545.1 sublancin immunity protein SunI -
B657_RS11700 2249900..2251150 - 1251 WP_004398504.1 UV-damage repair protein uvrX -
B657_RS11705 2251143..2251475 - 333 WP_004398710.1 YolD-like family protein -
B657_RS11710 2251649..2251984 + 336 WP_004399073.1 hypothetical protein -
B657_RS11715 2252027..2252383 - 357 WP_004398595.1 hypothetical protein -
B657_RS11720 2252389..2252856 - 468 WP_003246138.1 YolA family protein -
B657_RS22460 2253087..2253203 + 117 WP_009967548.1 type I toxin-antitoxin system toxin BsrG Toxin
- 2253198..2253377 - 180 NuclAT_0 - Antitoxin
- 2253198..2253377 - 180 NuclAT_0 - Antitoxin
- 2253198..2253377 - 180 NuclAT_0 - Antitoxin
- 2253198..2253377 - 180 NuclAT_0 - Antitoxin
B657_RS11730 2253482..2254015 - 534 WP_004399156.1 GNAT family N-acetyltransferase -
B657_RS11735 2254051..2254629 - 579 WP_004399123.1 SMI1/KNR4 family protein -
B657_RS11740 2254693..2255190 - 498 WP_003246188.1 SMI1/KNR4 family protein -
B657_RS11745 2255199..2256914 - 1716 WP_004398855.1 ribonuclease YeeF family protein -
B657_RS11750 2257014..2257571 - 558 WP_003246042.1 SMI1/KNR4 family protein -
B657_RS21990 2257655..2257840 + 186 WP_003245951.1 transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2131121..2265901 134780


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(1-38)


Sequences

Toxin        


Download         Length: 39 a.a.        Molecular weight: 4336.39 Da        Isoelectric Point: 10.1022

>T28197 WP_009967548.1 NC_018520:2253087-2253203 [Bacillus subtilis QB928]
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK

Download         Length: 117 bp

>T28197 NC_018520:2253087-2253203 [Bacillus subtilis QB928]
ATGACTGTTTACGAATCATTAATGATAATGATCAATTTTGGCGGATTGATATTAAATACCGTCTTGTTGATCTTCAATAT
AATGATGATTGTAACGTCAAGCCAAAAGAAAAAATAG

Antitoxin


Download         Length: 180 bp

>AT28197 NC_018520:c2253377-2253198 [Bacillus subtilis QB928]
AATGATACAATTATATAATTATTTTTTGCATTTTGTTTAATTAAATGCATAAAATAAAAAGACCAGGGTGTTGGTAGCAC
CCTGGCTCTGTACAAAAGCTGCCCATCAAAGGGCTTGCTCGTTGTCAAATCTGCGTAGGCCTAACCCTTCAGGTGTCCAA
ACTCAAGGGAAGGTCTATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7Z7EVU9

Antitoxin

Download structure file

References