Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) yonT-SR6/-
Location 2198815..2199144 Replicon chromosome
Accession NZ_AP024621
Organism Bacillus subtilis strain BEST3095

Toxin (Protein)


Gene name yonT Uniprot ID C0H439
Locus tag K6J89_RS11285 Protein ID WP_010886546.1
Coordinates 2198815..2199066 (-) Length 84 a.a.

Antitoxin (RNA)


Gene name SR6
Locus tag -
Coordinates 2199044..2199144 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6J89_RS11260 2194273..2194500 - 228 WP_004399298.1 helix-turn-helix transcriptional regulator -
K6J89_RS11265 2194761..2196077 - 1317 WP_004399369.1 hypothetical protein -
K6J89_RS11270 2196434..2196940 - 507 WP_004399486.1 hypothetical protein -
K6J89_RS11275 2197268..2198500 - 1233 WP_004399445.1 hypothetical protein -
K6J89_RS11280 2198582..2198770 - 189 WP_004399547.1 hypothetical protein -
K6J89_RS11285 2198815..2199066 - 252 WP_010886546.1 hypothetical protein Toxin
- 2199044..2199144 + 101 - - Antitoxin
K6J89_RS11290 2199085..2199261 - 177 WP_009967515.1 hypothetical protein -
- 2199202..2199302 + 101 NuclAT_2 - -
- 2199202..2199302 + 101 NuclAT_2 - -
- 2199202..2199302 + 101 NuclAT_2 - -
- 2199202..2199302 + 101 NuclAT_2 - -
K6J89_RS11295 2199636..2200247 - 612 WP_009967516.1 lipoprotein -
K6J89_RS11300 2200362..2200688 - 327 WP_009967517.1 helix-turn-helix transcriptional regulator -
K6J89_RS11305 2201641..2201835 + 195 WP_004399291.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2130929..2265709 134780


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9956.96 Da        Isoelectric Point: 9.7930

>T38966 WP_010886546.1 NZ_AP024621:c2199066-2198815 [Bacillus subtilis]
MNFSFSSYPYYNMIKHIANMKRFSLWFTHITFIGLFLMFQLIKDYFSSEGQALINTIFVVTCIIAILLWIIYCVFLKLRN
KSH

Download         Length: 252 bp

>T38966 NZ_AP024621:c2199066-2198815 [Bacillus subtilis]
ATGAACTTCTCCTTTAGTTCCTACCCATATTATAACATGATCAAGCACATTGCAAACATGAAACGATTCTCATTATGGTT
TACCCATATCACATTCATTGGCTTATTCTTAATGTTTCAACTCATCAAAGATTACTTCAGCAGCGAAGGACAGGCGCTAA
TCAACACAATTTTTGTTGTCACATGTATCATTGCCATATTGTTATGGATCATCTATTGTGTATTCCTTAAACTAAGAAAC
AAGTCACACTAA

Antitoxin


Download         Length: 101 bp

>AT38966 NZ_AP024621:2199044-2199144 [Bacillus subtilis]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCGGCGTATACGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB C0H439

Antitoxin

Download structure file

References