Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) yonT-SR6/-
Location 3955123..3955452 Replicon chromosome
Accession NZ_CP064095
Organism Bacillus subtilis strain N1303-2Ay

Toxin (Protein)


Gene name yonT Uniprot ID C0H439
Locus tag IRJ27_RS20635 Protein ID WP_010886546.1
Coordinates 3955201..3955452 (+) Length 84 a.a.

Antitoxin (RNA)


Gene name SR6
Locus tag -
Coordinates 3955123..3955223 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IRJ27_RS20615 3952432..3952626 - 195 WP_004399291.1 hypothetical protein -
IRJ27_RS20620 3953579..3953905 + 327 WP_009967517.1 helix-turn-helix transcriptional regulator -
IRJ27_RS20625 3954020..3954631 + 612 WP_009967516.1 lipoprotein -
- 3954965..3955065 - 101 NuclAT_2 - -
- 3954965..3955065 - 101 NuclAT_2 - -
- 3954965..3955065 - 101 NuclAT_2 - -
- 3954965..3955065 - 101 NuclAT_2 - -
IRJ27_RS20630 3955006..3955182 + 177 WP_009967515.1 hypothetical protein -
- 3955123..3955223 - 101 - - Antitoxin
IRJ27_RS20635 3955201..3955452 + 252 WP_010886546.1 hypothetical protein Toxin
IRJ27_RS20640 3955497..3955685 + 189 WP_004399547.1 hypothetical protein -
IRJ27_RS20645 3955767..3956999 + 1233 WP_004399445.1 hypothetical protein -
IRJ27_RS20650 3957327..3957833 + 507 WP_004399486.1 hypothetical protein -
IRJ27_RS20655 3958190..3959506 + 1317 WP_004399369.1 hypothetical protein -
IRJ27_RS20660 3959767..3959994 + 228 WP_004399298.1 helix-turn-helix transcriptional regulator -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 3874311..4023340 149029


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 84 a.a.        Molecular weight: 9956.96 Da        Isoelectric Point: 9.7930

>T180093 WP_010886546.1 NZ_CP064095:3955201-3955452 [Bacillus subtilis]
MNFSFSSYPYYNMIKHIANMKRFSLWFTHITFIGLFLMFQLIKDYFSSEGQALINTIFVVTCIIAILLWIIYCVFLKLRN
KSH

Download         Length: 252 bp

>T180093 NZ_CP085063:c2618738-2618448 [Escherichia coli]
ATGAACTATGAGCTGGCGTTTGATCCGCGGGCGCTGAAAGAGTGGCAAAAACTGGGCGTGACAGTCCGGGAACAATTTAA
AAAAAAGCTTGAGGATGTGCTGAAAAGGCCGCGCAATCCATCGGCTAAACTGCGGGATTTACCGGACTGCTACAAAATTA
AGCTGCGCACACAGGGATATCGCCTGGTTTATCAGGTTAACGATAAAGAGTTGCTCGTGTTGGTGATAGCTATTGGTAAG
AGAGAGAACTCAGCCGTTTATGAAGACGCGACTAAACGGCTGGATGAGTGA

Antitoxin


Download         Length: 101 bp

>AT180093 NZ_CP064095:c3955223-3955123 [Bacillus subtilis]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCGGCGTATACGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB C0H439


Antitoxin

Download structure file

References