Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) yonT-SR6/-
Location 2224116..2224445 Replicon chromosome
Accession NZ_CP089592
Organism Bacillus subtilis strain Bsi

Toxin (Protein)


Gene name yonT Uniprot ID C0H439
Locus tag LUV29_RS11445 Protein ID WP_010886546.1
Coordinates 2224116..2224367 (-) Length 84 a.a.

Antitoxin (RNA)


Gene name SR6
Locus tag -
Coordinates 2224345..2224445 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LUV29_RS11420 2219574..2219801 - 228 WP_004399298.1 helix-turn-helix transcriptional regulator -
LUV29_RS11425 2220062..2221378 - 1317 WP_004399369.1 hypothetical protein -
LUV29_RS11430 2221735..2222241 - 507 WP_004399486.1 hypothetical protein -
LUV29_RS11435 2222569..2223801 - 1233 WP_004399445.1 hypothetical protein -
LUV29_RS11440 2223883..2224071 - 189 WP_004399547.1 hypothetical protein -
LUV29_RS11445 2224116..2224367 - 252 WP_010886546.1 hypothetical protein Toxin
- 2224345..2224445 + 101 - - Antitoxin
LUV29_RS11450 2224386..2224562 - 177 WP_009967515.1 hypothetical protein -
- 2224503..2224603 + 101 NuclAT_2 - -
- 2224503..2224603 + 101 NuclAT_2 - -
- 2224503..2224603 + 101 NuclAT_2 - -
- 2224503..2224603 + 101 NuclAT_2 - -
LUV29_RS11455 2224937..2225548 - 612 WP_009967516.1 lipoprotein -
LUV29_RS11460 2225663..2225989 - 327 WP_009967517.1 helix-turn-helix transcriptional regulator -
LUV29_RS11465 2226942..2227136 + 195 WP_004399291.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2156228..2316487 160259


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 84 a.a.        Molecular weight: 9956.96 Da        Isoelectric Point: 9.7930

>T228394 WP_010886546.1 NZ_CP089592:c2224367-2224116 [Bacillus subtilis]
MNFSFSSYPYYNMIKHIANMKRFSLWFTHITFIGLFLMFQLIKDYFSSEGQALINTIFVVTCIIAILLWIIYCVFLKLRN
KSH

Download         Length: 252 bp

>T228394 NZ_CP123909:1123555-1123833 [Pseudomonas atacamensis]
ATGATCAAATCCTTTCAGCACAAAGGCCTTCGTGGCTTCTATGAAATAGGTACGACTCGTGGAATTCGTGCCGACCATGC
AAAACGGCTGTCGCGCATGTTGCAGTTCATGGATCGAGCGACACTTCCCGGCGATCTGGACTTGCCGGGCTGGCGCCTGC
ATCCGTTGAAAGGCGAGCTGAGTGAATACTGGTCGCTCAGCGTTTCAGGCAACTGGCGAGTGATCTTTCGTTTTGTCGGT
TCGGATATCGAATTGGTCGATTATCTGGACTACCACTGA

Antitoxin


Download         Length: 101 bp

>AT228394 NZ_CP089592:2224345-2224445 [Bacillus subtilis]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCGGCGTATACGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB C0H439


Antitoxin

Download structure file

References