Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) bsrG-as-bsrH/-
Location 2252895..2253185 Replicon chromosome
Accession NZ_AP024621
Organism Bacillus subtilis strain BEST3095

Toxin (Protein)


Gene name bsrG Uniprot ID L8EAY0
Locus tag K6J89_RS11585 Protein ID WP_009967548.1
Coordinates 2252895..2253011 (+) Length 39 a.a.

Antitoxin (RNA)


Gene name as-bsrH
Locus tag -
Coordinates 2253006..2253185 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6J89_RS11550 (2248822) 2248822..2248992 - 171 WP_009967544.1 bacteriocin sublancin-168 -
K6J89_RS11555 (2249289) 2249289..2249606 - 318 WP_009967545.1 sublancin immunity protein SunI -
K6J89_RS11560 (2249708) 2249708..2250958 - 1251 WP_004398504.1 UV-damage repair protein uvrX -
K6J89_RS11565 (2250951) 2250951..2251283 - 333 WP_004398710.1 YolD-like family protein -
K6J89_RS11570 (2251457) 2251457..2251792 + 336 WP_004399073.1 hypothetical protein -
K6J89_RS11575 (2251835) 2251835..2252191 - 357 WP_004398595.1 hypothetical protein -
K6J89_RS11580 (2252197) 2252197..2252664 - 468 WP_003246138.1 YolA family protein -
K6J89_RS11585 (2252895) 2252895..2253011 + 117 WP_009967548.1 type I toxin-antitoxin system toxin BsrG Toxin
- (2253006) 2253006..2253185 - 180 NuclAT_1 - Antitoxin
- (2253006) 2253006..2253185 - 180 NuclAT_1 - Antitoxin
- (2253006) 2253006..2253185 - 180 NuclAT_1 - Antitoxin
- (2253006) 2253006..2253185 - 180 NuclAT_1 - Antitoxin
K6J89_RS11590 (2253290) 2253290..2253823 - 534 WP_004399156.1 GNAT family protein -
K6J89_RS11595 (2253859) 2253859..2254437 - 579 WP_004399123.1 SMI1/KNR4 family protein -
K6J89_RS11600 (2254501) 2254501..2254998 - 498 WP_003246188.1 SMI1/KNR4 family protein -
K6J89_RS11605 (2255007) 2255007..2256722 - 1716 WP_004398855.1 ribonuclease YeeF family protein -
K6J89_RS11610 (2256822) 2256822..2257379 - 558 WP_003246042.1 SMI1/KNR4 family protein -
K6J89_RS11615 (2257514) 2257514..2257648 + 135 WP_234047931.1 transposase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2130929..2265709 134780


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(1-38)


Sequences


Toxin        


Download         Length: 39 a.a.        Molecular weight: 4336.39 Da        Isoelectric Point: 10.1022

>T38976 WP_009967548.1 NZ_AP024621:2252895-2253011 [Bacillus subtilis]
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK

Download         Length: 117 bp

>T38976 NZ_AP024621:2252895-2253011 [Bacillus subtilis]
ATGACTGTTTACGAATCATTAATGATAATGATCAATTTTGGCGGATTGATATTAAATACCGTCTTGTTGATCTTCAATAT
AATGATGATTGTAACGTCAAGCCAAAAGAAAAAATAG

Antitoxin


Download         Length: 180 bp

>AT38976 NZ_AP024621:c2253185-2253006 [Bacillus subtilis]
AATGATACAATTATATAATTATTTTTTGCATTTTGTTTAATTAAATGCATAAAATAAAAAGACCAGGGTGTTGGTAGCAC
CCTGGCTCTGTACAAAAGCTGCCCATCAAAGGGCTTGCTCGTTGTCAAATCTGCGTAGGCCTAACCCTTCAGGTGTCCAA
ACTCAAGGGAAGGTCTATTT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A7Z7EVU9


Antitoxin

Download structure file

References