Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) yonT-as-bsrG/-
Location 2185880..2186097 Replicon chromosome
Accession NZ_AP024625
Organism Bacillus subtilis strain BEST3109

Toxin (Protein)


Gene name yonT Uniprot ID O31941
Locus tag BsBEST3145_RS11215 Protein ID WP_009967515.1
Coordinates 2185880..2186056 (-) Length 59 a.a.

Antitoxin (RNA)


Gene name as-bsrG
Locus tag -
Coordinates 2185997..2186097 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BsBEST3145_RS11185 (2181068) 2181068..2181295 - 228 WP_004399298.1 helix-turn-helix transcriptional regulator -
BsBEST3145_RS11190 (2181556) 2181556..2182872 - 1317 WP_004399369.1 hypothetical protein -
BsBEST3145_RS11195 (2183229) 2183229..2183735 - 507 WP_004399486.1 hypothetical protein -
BsBEST3145_RS11200 (2184063) 2184063..2185295 - 1233 WP_004399445.1 hypothetical protein -
BsBEST3145_RS11205 (2185377) 2185377..2185565 - 189 WP_004399547.1 hypothetical protein -
BsBEST3145_RS11210 (2185610) 2185610..2185861 - 252 WP_010886546.1 hypothetical protein -
BsBEST3145_RS11215 (2185880) 2185880..2186056 - 177 WP_009967515.1 hypothetical protein Toxin
- (2185997) 2185997..2186097 + 101 NuclAT_2 - Antitoxin
- (2185997) 2185997..2186097 + 101 NuclAT_2 - Antitoxin
- (2185997) 2185997..2186097 + 101 NuclAT_2 - Antitoxin
- (2185997) 2185997..2186097 + 101 NuclAT_2 - Antitoxin
BsBEST3145_RS11220 (2186431) 2186431..2187042 - 612 WP_009967516.1 lipoprotein -
BsBEST3145_RS11225 (2187157) 2187157..2187483 - 327 WP_009967517.1 helix-turn-helix transcriptional regulator -
BsBEST3145_RS11230 (2188436) 2188436..2188630 + 195 WP_004399291.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2117724..2266751 149027


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6882.45 Da        Isoelectric Point: 12.8833

>T39064 WP_009967515.1 NZ_AP024625:c2186056-2185880 [Bacillus subtilis]
VLEKMGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Download         Length: 177 bp

>T39064 NZ_AP024625:c2186056-2185880 [Bacillus subtilis]
GTGCTTGAGAAAATGGGTATCGTAGTTGCTTTCCTCATATCTTTAACGGTTCTTACAATCAACAGTCTAACAATAGTTGA
GAAGGTAAGAAACCTAAAGAATGGGACAAGCAAAAAGAAAAAGCGTATACGCAAGCGGCTCCGACCAAAGAGACAACGCC
AACGTATACGCCGATGA

Antitoxin


Download         Length: 101 bp

>AT39064 NZ_AP024625:2185997-2186097 [Bacillus subtilis]
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTACGATACCCATTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB O31941

Antitoxin

Download structure file

References