Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) yonT-SR6/-
Location 2191292..2191621 Replicon chromosome
Accession NZ_AP024628
Organism Bacillus subtilis strain BEST3145

Toxin (Protein)


Gene name yonT Uniprot ID C0H439
Locus tag K6K00_RS11175 Protein ID WP_010886546.1
Coordinates 2191292..2191543 (-) Length 84 a.a.

Antitoxin (RNA)


Gene name SR6
Locus tag -
Coordinates 2191521..2191621 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6K00_RS11150 2186750..2186977 - 228 WP_004399298.1 helix-turn-helix transcriptional regulator -
K6K00_RS11155 2187238..2188554 - 1317 WP_004399369.1 hypothetical protein -
K6K00_RS11160 2188911..2189417 - 507 WP_004399486.1 hypothetical protein -
K6K00_RS11165 2189745..2190977 - 1233 WP_004399445.1 hypothetical protein -
K6K00_RS11170 2191059..2191247 - 189 WP_004399547.1 hypothetical protein -
K6K00_RS11175 2191292..2191543 - 252 WP_010886546.1 hypothetical protein Toxin
- 2191521..2191621 + 101 - - Antitoxin
K6K00_RS11180 2191562..2191738 - 177 WP_009967515.1 hypothetical protein -
- 2191679..2191779 + 101 NuclAT_2 - -
- 2191679..2191779 + 101 NuclAT_2 - -
- 2191679..2191779 + 101 NuclAT_2 - -
- 2191679..2191779 + 101 NuclAT_2 - -
K6K00_RS11185 2192113..2192724 - 612 WP_009967516.1 lipoprotein -
K6K00_RS11190 2192839..2193165 - 327 WP_009967517.1 helix-turn-helix transcriptional regulator -
K6K00_RS11195 2194118..2194312 + 195 WP_004399291.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2123406..2258186 134780


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9956.96 Da        Isoelectric Point: 9.7930

>T39127 WP_010886546.1 NZ_AP024628:c2191543-2191292 [Bacillus subtilis]
MNFSFSSYPYYNMIKHIANMKRFSLWFTHITFIGLFLMFQLIKDYFSSEGQALINTIFVVTCIIAILLWIIYCVFLKLRN
KSH

Download         Length: 252 bp

>T39127 NZ_AP024628:c2191543-2191292 [Bacillus subtilis]
ATGAACTTCTCCTTTAGTTCCTACCCATATTATAACATGATCAAGCACATTGCAAACATGAAACGATTCTCATTATGGTT
TACCCATATCACATTCATTGGCTTATTCTTAATGTTTCAACTCATCAAAGATTACTTCAGCAGCGAAGGACAGGCGCTAA
TCAACACAATTTTTGTTGTCACATGTATCATTGCCATATTGTTATGGATCATCTATTGTGTATTCCTTAAACTAAGAAAC
AAGTCACACTAA

Antitoxin


Download         Length: 101 bp

>AT39127 NZ_AP024628:2191521-2191621 [Bacillus subtilis]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCGGCGTATACGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB C0H439

Antitoxin

Download structure file

References