Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) yonT-as-bsrG/-
Location 2221324..2221811 Replicon chromosome
Accession NZ_CP112873
Organism Bacillus subtilis strain O4

Toxin (Protein)


Gene name yonT Uniprot ID C0H439
Locus tag ORF34_RS11465 Protein ID WP_010886546.1
Coordinates 2221324..2221575 (-) Length 84 a.a.

Antitoxin (RNA)


Gene name as-bsrG
Locus tag -
Coordinates 2221711..2221811 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ORF34_RS11440 (2216782) 2216782..2217009 - 228 WP_004399298.1 helix-turn-helix transcriptional regulator -
ORF34_RS11445 (2217270) 2217270..2218586 - 1317 WP_004399369.1 hypothetical protein -
ORF34_RS11450 (2218943) 2218943..2219449 - 507 WP_004399486.1 hypothetical protein -
ORF34_RS11455 (2219777) 2219777..2221009 - 1233 WP_004399445.1 hypothetical protein -
ORF34_RS11460 (2221091) 2221091..2221279 - 189 WP_004399547.1 hypothetical protein -
ORF34_RS11465 (2221324) 2221324..2221575 - 252 WP_010886546.1 hypothetical protein Toxin
ORF34_RS11470 (2221594) 2221594..2221770 - 177 WP_009967515.1 hypothetical protein -
- (2221711) 2221711..2221811 + 101 NuclAT_2 - Antitoxin
- (2221711) 2221711..2221811 + 101 NuclAT_2 - Antitoxin
- (2221711) 2221711..2221811 + 101 NuclAT_2 - Antitoxin
- (2221711) 2221711..2221811 + 101 NuclAT_2 - Antitoxin
ORF34_RS11475 (2222145) 2222145..2222756 - 612 WP_009967516.1 lipoprotein -
ORF34_RS11480 (2222871) 2222871..2223197 - 327 WP_009967517.1 helix-turn-helix transcriptional regulator -
ORF34_RS11485 (2224150) 2224150..2224344 + 195 WP_004399291.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2153436..2288218 134782


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9956.96 Da        Isoelectric Point: 9.7930

>T264905 WP_010886546.1 NZ_CP112873:c2221575-2221324 [Bacillus subtilis]
MNFSFSSYPYYNMIKHIANMKRFSLWFTHITFIGLFLMFQLIKDYFSSEGQALINTIFVVTCIIAILLWIIYCVFLKLRN
KSH

Download         Length: 252 bp

Antitoxin


Download         Length: 101 bp

>AT264905 NZ_CP112873:2221711-2221811 [Bacillus subtilis]
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTACGATACCCATTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB C0H439

Antitoxin

Download structure file

References