Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) bsrG-as-bsrH/-
Location 2246362..2246652 Replicon chromosome
Accession NZ_CP007800
Organism Bacillus subtilis subsp. subtilis str. JH642 substr. AG174 strain JH642

Toxin (Protein)


Gene name bsrG Uniprot ID L8EAY0
Locus tag BSUA_RS22800 Protein ID WP_009967548.1
Coordinates 2246362..2246478 (+) Length 39 a.a.

Antitoxin (RNA)


Gene name as-bsrH
Locus tag -
Coordinates 2246473..2246652 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BSUA_RS11725 2242289..2242459 - 171 WP_009967544.1 bacteriocin sublancin-168 -
BSUA_RS11730 2242756..2243073 - 318 WP_009967545.1 sublancin immunity protein SunI -
BSUA_RS11735 2243175..2244425 - 1251 WP_004398504.1 UV-damage repair protein uvrX -
BSUA_RS11740 2244418..2244750 - 333 WP_004398710.1 YolD-like family protein -
BSUA_RS11745 2244924..2245259 + 336 WP_004399073.1 hypothetical protein -
BSUA_RS11750 2245302..2245658 - 357 WP_004398595.1 hypothetical protein -
BSUA_RS11755 2245664..2246131 - 468 WP_003246138.1 YolA family protein -
BSUA_RS22800 2246362..2246478 + 117 WP_009967548.1 type I toxin-antitoxin system toxin BsrG Toxin
- 2246473..2246652 - 180 NuclAT_1 - Antitoxin
- 2246473..2246652 - 180 NuclAT_1 - Antitoxin
- 2246473..2246652 - 180 NuclAT_1 - Antitoxin
- 2246473..2246652 - 180 NuclAT_1 - Antitoxin
BSUA_RS11765 2246757..2247290 - 534 WP_004399156.1 GNAT family N-acetyltransferase -
BSUA_RS11770 2247326..2247904 - 579 WP_004399123.1 SMI1/KNR4 family protein -
BSUA_RS11775 2247968..2248465 - 498 WP_003246188.1 SMI1/KNR4 family protein -
BSUA_RS11780 2248474..2250189 - 1716 WP_004398855.1 ribonuclease YeeF family protein -
BSUA_RS11785 2250289..2250846 - 558 WP_003246042.1 SMI1/KNR4 family protein -
BSUA_RS22370 2250930..2251115 + 186 WP_003245951.1 transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2124394..2259176 134782


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(1-38)


Sequences

Toxin        


Download         Length: 39 a.a.        Molecular weight: 4336.39 Da        Isoelectric Point: 10.1022

>T47073 WP_009967548.1 NZ_CP007800:2246362-2246478 [Bacillus subtilis subsp. subtilis str. JH642 substr. AG174]
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK

Download         Length: 117 bp

>T47073 NZ_CP007800:2246362-2246478 [Bacillus subtilis subsp. subtilis str. JH642 substr. AG174]
ATGACTGTTTACGAATCATTAATGATAATGATCAATTTTGGCGGATTGATATTAAATACCGTCTTGTTGATCTTCAATAT
AATGATGATTGTAACGTCAAGCCAAAAGAAAAAATAG

Antitoxin


Download         Length: 180 bp

>AT47073 NZ_CP007800:c2246652-2246473 [Bacillus subtilis subsp. subtilis str. JH642 substr. AG174]
AATGATACAATTATATAATTATTTTTTGCATTTTGTTTAATTAAATGCATAAAATAAAAAGACCAGGGTGTTGGTAGCAC
CCTGGCTCTGTACAAAAGCTGCCCATCAAAGGGCTTGCTCGTTGTCAAATCTGCGTAGGCCTAACCCTTCAGGTGTCCAA
ACTCAAGGGAAGGTCTATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7Z7EVU9

Antitoxin

Download structure file

References