Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) yonT-SR6/-
Location 2199006..2199335 Replicon chromosome
Accession NZ_CP010314
Organism Bacillus subtilis subsp. subtilis strain 3NA isolate 1970 (Michel and Millet)

Toxin (Protein)


Gene name yonT Uniprot ID C0H439
Locus tag RP72_RS22640 Protein ID WP_010886546.1
Coordinates 2199006..2199257 (-) Length 84 a.a.

Antitoxin (RNA)


Gene name SR6
Locus tag -
Coordinates 2199235..2199335 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RP72_RS11395 2194464..2194691 - 228 WP_004399298.1 helix-turn-helix transcriptional regulator -
RP72_RS11400 2194952..2196268 - 1317 WP_004399369.1 hypothetical protein -
RP72_RS11405 2196625..2197131 - 507 WP_004399486.1 hypothetical protein -
RP72_RS11410 2197459..2198691 - 1233 WP_004399445.1 hypothetical protein -
RP72_RS11415 2198773..2198961 - 189 WP_004399547.1 hypothetical protein -
RP72_RS22640 2199006..2199257 - 252 WP_010886546.1 hypothetical protein Toxin
- 2199235..2199335 + 101 - - Antitoxin
RP72_RS22645 2199276..2199452 - 177 WP_009967515.1 hypothetical protein -
- 2199393..2199493 + 101 NuclAT_2 - -
- 2199393..2199493 + 101 NuclAT_2 - -
- 2199393..2199493 + 101 NuclAT_2 - -
- 2199393..2199493 + 101 NuclAT_2 - -
RP72_RS11425 2199827..2200438 - 612 WP_009967516.1 lipoprotein -
RP72_RS11430 2200553..2200879 - 327 WP_009967517.1 helix-turn-helix domain-containing protein -
RP72_RS11435 2201832..2202026 + 195 WP_004399291.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2131118..2265900 134782


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9956.96 Da        Isoelectric Point: 9.7930

>T51995 WP_010886546.1 NZ_CP010314:c2199257-2199006 [Bacillus subtilis subsp. subtilis]
MNFSFSSYPYYNMIKHIANMKRFSLWFTHITFIGLFLMFQLIKDYFSSEGQALINTIFVVTCIIAILLWIIYCVFLKLRN
KSH

Download         Length: 252 bp

>T51995 NZ_CP010314:c2199257-2199006 [Bacillus subtilis subsp. subtilis]
ATGAACTTCTCCTTTAGTTCCTACCCATATTATAACATGATCAAGCACATTGCAAACATGAAACGATTCTCATTATGGTT
TACCCATATCACATTCATTGGCTTATTCTTAATGTTTCAACTCATCAAAGATTACTTCAGCAGCGAAGGACAGGCGCTAA
TCAACACAATTTTTGTTGTCACATGTATCATTGCCATATTGTTATGGATCATCTATTGTGTATTCCTTAAACTAAGAAAC
AAGTCACACTAA

Antitoxin


Download         Length: 101 bp

>AT51995 NZ_CP010314:2199235-2199335 [Bacillus subtilis subsp. subtilis]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCGGCGTATACGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB C0H439

Antitoxin

Download structure file

References