Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) yonT-SR6/-
Location 2219520..2219849 Replicon chromosome
Accession NZ_CP011115
Organism Bacillus subtilis KCTC 1028 = ATCC 6051a strain KCTC 1028

Toxin (Protein)


Gene name yonT Uniprot ID C0H439
Locus tag O7A_RS22750 Protein ID WP_010886546.1
Coordinates 2219520..2219771 (-) Length 84 a.a.

Antitoxin (RNA)


Gene name SR6
Locus tag -
Coordinates 2219749..2219849 (+)

Genomic Context

------O7A_RS11545O7A_RS11505O7A_RS11510O7A_RS11515O7A_RS11520O7A_RS11525O7A_RS22750O7A_RS22755O7A_RS11535O7A_RS11540
Location: 2219749..2219849 (101 bp)
Type: Antitoxin
Protein ID: -
Location: 2219907..2220007 (101 bp)
Type: Others
Protein ID: NuclAT_2
Location: 2219907..2220007 (101 bp)
Type: Others
Protein ID: NuclAT_2
Location: 2219907..2220007 (101 bp)
Type: Others
Protein ID: NuclAT_2
Location: 2219907..2220007 (101 bp)
Type: Others
Protein ID: NuclAT_2
Location: 2222346..2222540 (195 bp)
Type: Others
Protein ID: WP_004399291.1
Location: 2214978..2215205 (228 bp)
Type: Others
Protein ID: WP_004399298.1
Location: 2215466..2216782 (1317 bp)
Type: Others
Protein ID: WP_004399369.1
Location: 2217139..2217645 (507 bp)
Type: Others
Protein ID: WP_004399486.1
Location: 2217973..2219205 (1233 bp)
Type: Others
Protein ID: WP_004399445.1
Location: 2219287..2219475 (189 bp)
Type: Others
Protein ID: WP_004399547.1
Location: 2219520..2219771 (252 bp)
Type: Toxin
Protein ID: WP_010886546.1
Location: 2219790..2219966 (177 bp)
Type: Others
Protein ID: WP_009967515.1
Location: 2220341..2220952 (612 bp)
Type: Others
Protein ID: WP_009967516.1
Location: 2221067..2221393 (327 bp)
Type: Others
Protein ID: WP_009967517.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
O7A_RS115052214978..2215205-228WP_004399298.1helix-turn-helix transcriptional regulator-
O7A_RS115102215466..2216782-1317WP_004399369.1hypothetical protein-
O7A_RS115152217139..2217645-507WP_004399486.1hypothetical protein-
O7A_RS115202217973..2219205-1233WP_004399445.1hypothetical protein-
O7A_RS115252219287..2219475-189WP_004399547.1hypothetical protein-
O7A_RS227502219520..2219771-252WP_010886546.1hypothetical proteinToxin
-2219749..2219849+101--Antitoxin
O7A_RS227552219790..2219966-177WP_009967515.1hypothetical protein-
-2219907..2220007+101NuclAT_2--
-2219907..2220007+101NuclAT_2--
-2219907..2220007+101NuclAT_2--
-2219907..2220007+101NuclAT_2--
O7A_RS115352220341..2220952-612WP_009967516.1lipoprotein-
O7A_RS115402221067..2221393-327WP_009967517.1helix-turn-helix domain-containing protein-
O7A_RS115452222346..2222540+195WP_004399291.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
insideProphage--2151632..2286414134782


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9956.96 Da        Isoelectric Point: 9.7930

>T53432 WP_010886546.1 NZ_CP011115:c2219771-2219520 [Bacillus subtilis KCTC 1028 = ATCC 6051a]
MNFSFSSYPYYNMIKHIANMKRFSLWFTHITFIGLFLMFQLIKDYFSSEGQALINTIFVVTCIIAILLWIIYCVFLKLRN
KSH

Download         Length: 252 bp

>T53432 NZ_CP011115:c2219771-2219520 [Bacillus subtilis KCTC 1028 = ATCC 6051a]
ATGAACTTCTCCTTTAGTTCCTACCCATATTATAACATGATCAAGCACATTGCAAACATGAAACGATTCTCATTATGGTT
TACCCATATCACATTCATTGGCTTATTCTTAATGTTTCAACTCATCAAAGATTACTTCAGCAGCGAAGGACAGGCGCTAA
TCAACACAATTTTTGTTGTCACATGTATCATTGCCATATTGTTATGGATCATCTATTGTGTATTCCTTAAACTAAGAAAC
AAGTCACACTAA

Antitoxin


Download         Length: 101 bp

>AT53432 NZ_CP011115:2219749-2219849 [Bacillus subtilis KCTC 1028 = ATCC 6051a]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCGGCGTATACGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBC0H439

Antitoxin

Download structure file

References