Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) yonT-SR6/-
Location 2199236..2199453 Replicon chromosome
Accession NC_018520
Organism Bacillus subtilis QB928

Toxin (Protein)


Gene name yonT Uniprot ID O31941
Locus tag B657_RS11435 Protein ID WP_009967515.1
Coordinates 2199277..2199453 (-) Length 59 a.a.

Antitoxin (RNA)


Gene name SR6
Locus tag -
Coordinates 2199236..2199336 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B657_RS11410 2194465..2194692 - 228 WP_004399298.1 helix-turn-helix transcriptional regulator -
B657_RS11415 2194953..2196269 - 1317 WP_004399369.1 hypothetical protein -
B657_RS11420 2196626..2197132 - 507 WP_004399486.1 hypothetical protein -
B657_RS11425 2197460..2198692 - 1233 WP_004399445.1 hypothetical protein -
B657_RS11430 2198774..2198962 - 189 WP_004399547.1 hypothetical protein -
B657_RS21985 2199007..2199258 - 252 WP_010886546.1 hypothetical protein -
- 2199236..2199336 + 101 - - Antitoxin
B657_RS11435 2199277..2199453 - 177 WP_009967515.1 hypothetical protein Toxin
- 2199394..2199494 + 101 NuclAT_1 - -
- 2199394..2199494 + 101 NuclAT_1 - -
- 2199394..2199494 + 101 NuclAT_1 - -
- 2199394..2199494 + 101 NuclAT_1 - -
B657_RS11440 2199828..2200439 - 612 WP_009967516.1 lipoprotein -
B657_RS11445 2200554..2200880 - 327 WP_009967517.1 helix-turn-helix domain-containing protein -
B657_RS11450 2201833..2202027 + 195 WP_004399291.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2131121..2265901 134780


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RelA/SpoT

(76-174)


Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6882.45 Da        Isoelectric Point: 12.8833

>T28190 WP_009967515.1 NC_018520:c2199453-2199277 [Bacillus subtilis QB928]
VLEKMGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Download         Length: 177 bp

>T28190 NC_018520:c2199453-2199277 [Bacillus subtilis QB928]
GTGCTTGAGAAAATGGGTATCGTAGTTGCTTTCCTCATATCTTTAACGGTTCTTACAATCAACAGTCTAACAATAGTTGA
GAAGGTAAGAAACCTAAAGAATGGGACAAGCAAAAAGAAAAAGCGTATACGCAAGCGGCTCCGACCAAAGAGACAACGCC
AACGTATACGCCGATGA

Antitoxin


Download         Length: 101 bp

>AT28190 NC_018520:2199236-2199336 [Bacillus subtilis QB928]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCGGCGTATACGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB O31941

Antitoxin

Download structure file

References