Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) yonT-as-bsrG/-
Location 2213085..2213302 Replicon chromosome
Accession NZ_CP050532
Organism Bacillus subtilis subsp. subtilis str. SMY

Toxin (Protein)


Gene name yonT Uniprot ID O31941
Locus tag HCN55_RS11360 Protein ID WP_009967515.1
Coordinates 2213085..2213261 (-) Length 59 a.a.

Antitoxin (RNA)


Gene name as-bsrG
Locus tag -
Coordinates 2213202..2213302 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HCN55_RS11330 2208273..2208500 - 228 WP_004399298.1 helix-turn-helix transcriptional regulator -
HCN55_RS11335 2208761..2210077 - 1317 WP_004399369.1 hypothetical protein -
HCN55_RS11340 2210434..2210940 - 507 WP_004399486.1 hypothetical protein -
HCN55_RS11345 2211268..2212500 - 1233 WP_004399445.1 hypothetical protein -
HCN55_RS11350 2212582..2212770 - 189 WP_004399547.1 hypothetical protein -
HCN55_RS11355 2212815..2213066 - 252 WP_010886546.1 hypothetical protein -
HCN55_RS11360 2213085..2213261 - 177 WP_009967515.1 hypothetical protein Toxin
- 2213202..2213302 + 101 NuclAT_2 - Antitoxin
- 2213202..2213302 + 101 NuclAT_2 - Antitoxin
- 2213202..2213302 + 101 NuclAT_2 - Antitoxin
- 2213202..2213302 + 101 NuclAT_2 - Antitoxin
HCN55_RS11365 2213636..2214247 - 612 WP_009967516.1 lipoprotein -
HCN55_RS11370 2214362..2214688 - 327 WP_009967517.1 helix-turn-helix domain-containing protein -
HCN55_RS11375 2215641..2215835 + 195 WP_004399291.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2144927..2279709 134782


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6882.45 Da        Isoelectric Point: 12.8833

>T153030 WP_009967515.1 NZ_CP050532:c2213261-2213085 [Bacillus subtilis subsp. subtilis str. SMY]
VLEKMGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Download         Length: 177 bp

>T153030 NZ_CP066748:c659096-658632 [Escherichia coli O157:H7]
ATGGATTTTCCACAAAGGGTTAATGGTTGGGCGCTATATGCTCATCCCTGTTTTCAGGAAACCTACGACGCTTTAGTTGC
CGAAGTCGAGACATTAAAGGGAAAAGATCCTGAAAATTATCAGAGAAAAGCTGCCACAAAGTTATTGGCGGTGGTCCATA
AAGTGATTGAGGAGCATATCACGGTCAATCCATCATCACCGGCATTCCGTCATGGCAAGTCGTTAGGCTCTGGGAAAAAT
AAAGACTGGTCACGGGTAAAATTTGGTGCTGGTCGCTATCGTCTCTTCTTTCGTTACAGTGAAAAAGAGAAAGTCATCAT
TCTGGGATGGATGAACGATGAAAACACGCTGCGCACCTACGGTAAAAAAACAGATGCCTATACCGTATTCAGCAAAATGT
TAAAAAGAGGACATCCTCCTGCCGACTGGGAAACCCTCACCCGAGAGACAGAAGAAACCCATTGA

Antitoxin


Download         Length: 101 bp

>AT153030 NZ_CP050532:2213202-2213302 [Bacillus subtilis subsp. subtilis str. SMY]
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTACGATACCCATTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB O31941

Antitoxin

Download structure file

References