Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) yonT-SR6/-
Location 2214967..2215184 Replicon chromosome
Accession NZ_CP094361
Organism Bacillus subtilis strain NCIB 3610

Toxin (Protein)


Gene name yonT Uniprot ID O31941
Locus tag MQC90_RS11450 Protein ID WP_009967515.1
Coordinates 2215008..2215184 (-) Length 59 a.a.

Antitoxin (RNA)


Gene name SR6
Locus tag -
Coordinates 2214967..2215067 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MQC90_RS11420 2210196..2210423 - 228 WP_004399298.1 helix-turn-helix transcriptional regulator -
MQC90_RS11425 2210684..2212000 - 1317 WP_004399369.1 hypothetical protein -
MQC90_RS11430 2212357..2212863 - 507 WP_004399486.1 hypothetical protein -
MQC90_RS11435 2213191..2214423 - 1233 WP_004399445.1 hypothetical protein -
MQC90_RS11440 2214505..2214693 - 189 WP_004399547.1 hypothetical protein -
MQC90_RS11445 2214738..2214989 - 252 WP_010886546.1 hypothetical protein -
- 2214967..2215067 + 101 - - Antitoxin
MQC90_RS11450 2215008..2215184 - 177 WP_009967515.1 hypothetical protein Toxin
- 2215125..2215225 + 101 NuclAT_2 - -
- 2215125..2215225 + 101 NuclAT_2 - -
- 2215125..2215225 + 101 NuclAT_2 - -
- 2215125..2215225 + 101 NuclAT_2 - -
MQC90_RS11455 2215559..2216170 - 612 WP_009967516.1 lipoprotein -
MQC90_RS11460 2216285..2216611 - 327 WP_009967517.1 helix-turn-helix transcriptional regulator -
MQC90_RS11465 2217564..2217758 + 195 WP_004399291.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2146850..2307109 160259


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6882.45 Da        Isoelectric Point: 12.8833

>T239790 WP_009967515.1 NZ_CP094361:c2215184-2215008 [Bacillus subtilis]
VLEKMGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Download         Length: 177 bp

>T239790 NZ_LS483319:c2628912-2628805 [Staphylococcus aureus]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTATAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 101 bp

>AT239790 NZ_CP094361:2214967-2215067 [Bacillus subtilis]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCGGCGTATACGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB O31941

Antitoxin

Download structure file

References