Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) yonT-as-bsrG/-
Location 2224386..2224603 Replicon chromosome
Accession NZ_CP089592
Organism Bacillus subtilis strain Bsi

Toxin (Protein)


Gene name yonT Uniprot ID O31941
Locus tag LUV29_RS11450 Protein ID WP_009967515.1
Coordinates 2224386..2224562 (-) Length 59 a.a.

Antitoxin (RNA)


Gene name as-bsrG
Locus tag -
Coordinates 2224503..2224603 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LUV29_RS11420 (2219574) 2219574..2219801 - 228 WP_004399298.1 helix-turn-helix transcriptional regulator -
LUV29_RS11425 (2220062) 2220062..2221378 - 1317 WP_004399369.1 hypothetical protein -
LUV29_RS11430 (2221735) 2221735..2222241 - 507 WP_004399486.1 hypothetical protein -
LUV29_RS11435 (2222569) 2222569..2223801 - 1233 WP_004399445.1 hypothetical protein -
LUV29_RS11440 (2223883) 2223883..2224071 - 189 WP_004399547.1 hypothetical protein -
LUV29_RS11445 (2224116) 2224116..2224367 - 252 WP_010886546.1 hypothetical protein -
LUV29_RS11450 (2224386) 2224386..2224562 - 177 WP_009967515.1 hypothetical protein Toxin
- (2224503) 2224503..2224603 + 101 NuclAT_2 - Antitoxin
- (2224503) 2224503..2224603 + 101 NuclAT_2 - Antitoxin
- (2224503) 2224503..2224603 + 101 NuclAT_2 - Antitoxin
- (2224503) 2224503..2224603 + 101 NuclAT_2 - Antitoxin
LUV29_RS11455 (2224937) 2224937..2225548 - 612 WP_009967516.1 lipoprotein -
LUV29_RS11460 (2225663) 2225663..2225989 - 327 WP_009967517.1 helix-turn-helix transcriptional regulator -
LUV29_RS11465 (2226942) 2226942..2227136 + 195 WP_004399291.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2156228..2316487 160259


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-88)


Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6882.45 Da        Isoelectric Point: 12.8833

>T228400 WP_009967515.1 NZ_CP089592:c2224562-2224386 [Bacillus subtilis]
VLEKMGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Download         Length: 177 bp

>T228400 NZ_CP123909:c3926185-3925916 [Pseudomonas atacamensis]
ATGCAGATTGAGTGGCGGCCCGAAGCCAAGGCCGATCTTTCGAACATCCTCAGATACATTGGCGAGAGAAACTTCGCAGC
CGCAGTGAGTCTCTCGAAATCCATCGAAGAATCCACAACCTCACTCTCCGTTCATCCCCATCTCTACCGTAAAGGTCGAT
CTCCCGGCACCCGGGAAATCGTTGTACATCCTAACTACGTAGTGATTTATGAGGTGACGGATCGAGTCGAGATACTTAGC
GTTTTGCATACCCGACAGGAATATCCATAA

Antitoxin


Download         Length: 101 bp

>AT228400 NZ_CP089592:2224503-2224603 [Bacillus subtilis]
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTACGATACCCATTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB O31941

Antitoxin

Download structure file

References