Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) bsrG-as-bsrH/-
Location 2278196..2278486 Replicon chromosome
Accession NZ_CP089592
Organism Bacillus subtilis strain Bsi

Toxin (Protein)


Gene name bsrG Uniprot ID L8EAY0
Locus tag LUV29_RS11745 Protein ID WP_009967548.1
Coordinates 2278196..2278312 (+) Length 39 a.a.

Antitoxin (RNA)


Gene name as-bsrH
Locus tag -
Coordinates 2278307..2278486 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LUV29_RS11710 (2274123) 2274123..2274293 - 171 WP_009967544.1 bacteriocin sublancin-168 -
LUV29_RS11715 (2274590) 2274590..2274907 - 318 WP_009967545.1 sublancin immunity protein SunI -
LUV29_RS11720 (2275009) 2275009..2276259 - 1251 WP_004398504.1 UV-damage repair protein uvrX -
LUV29_RS11725 (2276252) 2276252..2276584 - 333 WP_004398710.1 YolD-like family protein -
LUV29_RS11730 (2276758) 2276758..2277093 + 336 WP_004399073.1 hypothetical protein -
LUV29_RS11735 (2277136) 2277136..2277492 - 357 WP_004398595.1 hypothetical protein -
LUV29_RS11740 (2277498) 2277498..2277965 - 468 WP_003246138.1 YolA family protein -
LUV29_RS11745 (2278196) 2278196..2278312 + 117 WP_009967548.1 type I toxin-antitoxin system toxin BsrG Toxin
- (2278307) 2278307..2278486 - 180 NuclAT_1 - Antitoxin
- (2278307) 2278307..2278486 - 180 NuclAT_1 - Antitoxin
- (2278307) 2278307..2278486 - 180 NuclAT_1 - Antitoxin
- (2278307) 2278307..2278486 - 180 NuclAT_1 - Antitoxin
LUV29_RS11750 (2278591) 2278591..2279124 - 534 WP_004399156.1 GNAT family protein -
LUV29_RS11755 (2279160) 2279160..2279738 - 579 WP_004399123.1 SMI1/KNR4 family protein -
LUV29_RS11760 (2279802) 2279802..2280299 - 498 WP_003246188.1 SMI1/KNR4 family protein -
LUV29_RS11765 (2280308) 2280308..2282023 - 1716 WP_004398855.1 ribonuclease YeeF family protein -
LUV29_RS11770 (2282123) 2282123..2282680 - 558 WP_003246042.1 SMI1/KNR4 family protein -
LUV29_RS11775 (2282815) 2282815..2282949 + 135 WP_234047931.1 transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2156228..2316487 160259


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(1-38)


Sequences

Toxin        


Download         Length: 39 a.a.        Molecular weight: 4336.39 Da        Isoelectric Point: 10.1022

>T228404 WP_009967548.1 NZ_CP089592:2278196-2278312 [Bacillus subtilis]
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK

Download         Length: 117 bp

>T228404 NZ_CP123909:c5670118-5669756 [Pseudomonas atacamensis]
ATGGTGCGCCGACAGCCCCCTCAGCGGGGTGACGTTTACTGGATTGATCCAAACCCAGTGGCGGGGCGGGAGATGATGAA
CAGACATCGCTTTGTGGTGATCACGCCCAGAGAGATCAACGCATTGGGCGTGAGCATGACGGTGCCTGTTACTGGCGGTG
GGAATTTCAGCCGGAATATGGGTTTGGCGGTCGCCATTACTGGCCACGAAACCAATGGTGTAGCGGTGTGTAATCAGGTT
CGCAGTTTTGACATAGAACAACGGGTACGAGACGGCACGGCCAAATTCATCGAGCGACTGGATGACGTGACAATGTCTGA
CATCGTCGACCGTGTAATCAGTGCAATCGACCCGCTAAGCTGA

Antitoxin


Download         Length: 180 bp

>AT228404 NZ_CP089592:c2278486-2278307 [Bacillus subtilis]
AATGATACAATTATATAATTATTTTTTGCATTTTGTTTAATTAAATGCATAAAATAAAAAGACCAGGGTGTTGGTAGCAC
CCTGGCTCTGTACAAAAGCTGCCCATCAAAGGGCTTGCTCGTTGTCAAATCTGCGTAGGCCTAACCCTTCAGGTGTCCAA
ACTCAAGGGAAGGTCTATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7Z7EVU9

Antitoxin

Download structure file

References