Detailed information of TA system
Overview
TA module
| Type | I | Classification (family/domain) | bsrG-as-bsrH/- |
| Location | 2273191..2273481 | Replicon | chromosome |
| Accession | NZ_CP082924 | ||
| Organism | Bacillus subtilis strain FJAT-4 | ||
Toxin (Protein)
| Gene name | bsrG | Uniprot ID | L8EAY0 |
| Locus tag | K8U58_RS11730 | Protein ID | WP_009967548.1 |
| Coordinates | 2273191..2273307 (+) | Length | 39 a.a. |
Antitoxin (RNA)
| Gene name | as-bsrH | ||
| Locus tag | - | ||
| Coordinates | 2273302..2273481 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| K8U58_RS11695 (2269118) | 2269118..2269288 | - | 171 | WP_009967544.1 | bacteriocin sublancin-168 | - |
| K8U58_RS11700 (2269585) | 2269585..2269902 | - | 318 | WP_009967545.1 | sublancin immunity protein SunI | - |
| K8U58_RS11705 (2270004) | 2270004..2271254 | - | 1251 | WP_004398504.1 | UV-damage repair protein uvrX | - |
| K8U58_RS11710 (2271247) | 2271247..2271579 | - | 333 | WP_004398710.1 | YolD-like family protein | - |
| K8U58_RS11715 (2271753) | 2271753..2272088 | + | 336 | WP_004399073.1 | hypothetical protein | - |
| K8U58_RS11720 (2272131) | 2272131..2272487 | - | 357 | WP_004398595.1 | hypothetical protein | - |
| K8U58_RS11725 (2272493) | 2272493..2272960 | - | 468 | WP_003246138.1 | YolA family protein | - |
| K8U58_RS11730 (2273191) | 2273191..2273307 | + | 117 | WP_009967548.1 | type I toxin-antitoxin system toxin BsrG | Toxin |
| - (2273302) | 2273302..2273481 | - | 180 | NuclAT_1 | - | Antitoxin |
| - (2273302) | 2273302..2273481 | - | 180 | NuclAT_1 | - | Antitoxin |
| - (2273302) | 2273302..2273481 | - | 180 | NuclAT_1 | - | Antitoxin |
| - (2273302) | 2273302..2273481 | - | 180 | NuclAT_1 | - | Antitoxin |
| K8U58_RS11735 (2273586) | 2273586..2274119 | - | 534 | WP_004399156.1 | GNAT family protein | - |
| K8U58_RS11740 (2274155) | 2274155..2274733 | - | 579 | WP_004399123.1 | SMI1/KNR4 family protein | - |
| K8U58_RS11745 (2274797) | 2274797..2275294 | - | 498 | WP_003246188.1 | SMI1/KNR4 family protein | - |
| K8U58_RS11750 (2275303) | 2275303..2277018 | - | 1716 | WP_004398855.1 | ribonuclease YeeF family protein | - |
| K8U58_RS11755 (2277118) | 2277118..2277675 | - | 558 | WP_003246042.1 | SMI1/KNR4 family protein | - |
| K8U58_RS11760 (2277810) | 2277810..2277944 | + | 135 | WP_234047931.1 | transposase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| inside | Prophage | - | - | 2151226..2286650 | 135424 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 39 a.a. Molecular weight: 4336.39 Da Isoelectric Point: 10.1022
>T215609 WP_009967548.1 NZ_CP082924:2273191-2273307 [Bacillus subtilis]
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK
Download Length: 117 bp
>T215609 NZ_CP110847:c1242120-1241374 [Bacillus velezensis]
ATGCTTTTGTTTTTTCAGATCATGGTGTGGACGATGGCGGCCGCACTCATTTTATATGTGTACGCATCCTGGCGGTATGA
GGCAAAGGTGAAAGAAAAAATGTTTGCCATCCGTAAAACGTGGTATTTACTATTTGTACTGGGCTCCATGGTCTATTGGA
CATATGATCCTGAATCGCTCTTTGCCGCATGGAGACAATATTTGATTGTTGCCGTCTGCTTTGCCCTTATTGATGCGTTT
ATCTTTTTGAGCGCGTATATCAAAAAGCTCGCCGGCAATGAATTAGAGACGGATACGCGGGAAATTTTAGAAGAAAATAA
CGAAATGCTTCACTCCTATCTTGAAAAACTGAAAACCTATCAATATCTGTTGAAAAATGAACCGATCCATGTATATTATG
GAAGTACAGAAGCTTATGCGGAAGGCATCAGCAGACTGCTGGCCGCTTATGCCGAAAAAATGAATGTCACGGCTTCCTTG
TGCGACTATTCCGCACAATCGGATAAGGACCGCTTGACGGAGCATATGCCTGATGCGGCAGACGTTCAGTCCCGTCTTAA
CCGTAAAGACGTCTACTATGATCAAAAAGGCAGGCTTGTGCTTATTCCGTTTACAGTCCAGAACCGCCATTACGTGATCA
AACTCACGTCGGAAAACCTGTTGACGGAATTCGATTATTTGCTTTTCACATCGCTAACGAGCATTTATGATTTAATGCTG
CCAATAGAAGAGGAAGGTGACGGTTAA
ATGCTTTTGTTTTTTCAGATCATGGTGTGGACGATGGCGGCCGCACTCATTTTATATGTGTACGCATCCTGGCGGTATGA
GGCAAAGGTGAAAGAAAAAATGTTTGCCATCCGTAAAACGTGGTATTTACTATTTGTACTGGGCTCCATGGTCTATTGGA
CATATGATCCTGAATCGCTCTTTGCCGCATGGAGACAATATTTGATTGTTGCCGTCTGCTTTGCCCTTATTGATGCGTTT
ATCTTTTTGAGCGCGTATATCAAAAAGCTCGCCGGCAATGAATTAGAGACGGATACGCGGGAAATTTTAGAAGAAAATAA
CGAAATGCTTCACTCCTATCTTGAAAAACTGAAAACCTATCAATATCTGTTGAAAAATGAACCGATCCATGTATATTATG
GAAGTACAGAAGCTTATGCGGAAGGCATCAGCAGACTGCTGGCCGCTTATGCCGAAAAAATGAATGTCACGGCTTCCTTG
TGCGACTATTCCGCACAATCGGATAAGGACCGCTTGACGGAGCATATGCCTGATGCGGCAGACGTTCAGTCCCGTCTTAA
CCGTAAAGACGTCTACTATGATCAAAAAGGCAGGCTTGTGCTTATTCCGTTTACAGTCCAGAACCGCCATTACGTGATCA
AACTCACGTCGGAAAACCTGTTGACGGAATTCGATTATTTGCTTTTCACATCGCTAACGAGCATTTATGATTTAATGCTG
CCAATAGAAGAGGAAGGTGACGGTTAA
Antitoxin
Download Length: 180 bp
>AT215609 NZ_CP082924:c2273481-2273302 [Bacillus subtilis]
AATGATACAATTATATAATTATTTTTTGCATTTTGTTTAATTAAATGCATAAAATAAAAAGACCAGGGTGTTGGTAGCAC
CCTGGCTCTGTACAAAAGCTGCCCATCAAAGGGCTTGCTCGTTGTCAAATCTGCGTAGGCCTAACCCTTCAGGTGTCCAA
ACTCAAGGGAAGGTCTATTT
AATGATACAATTATATAATTATTTTTTGCATTTTGTTTAATTAAATGCATAAAATAAAAAGACCAGGGTGTTGGTAGCAC
CCTGGCTCTGTACAAAAGCTGCCCATCAAAGGGCTTGCTCGTTGTCAAATCTGCGTAGGCCTAACCCTTCAGGTGTCCAA
ACTCAAGGGAAGGTCTATTT
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
