Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) yonT-SR6/-
Location 2219274..2219603 Replicon chromosome
Accession NZ_CP010053
Organism Bacillus subtilis strain PS832

Toxin (Protein)


Gene name yonT Uniprot ID C0H439
Locus tag QX56_RS21765 Protein ID WP_010886546.1
Coordinates 2219274..2219525 (-) Length 84 a.a.

Antitoxin (RNA)


Gene name SR6
Locus tag -
Coordinates 2219503..2219603 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QX56_RS10955 2214732..2214959 - 228 WP_004399298.1 helix-turn-helix transcriptional regulator -
QX56_RS10960 2215220..2216536 - 1317 WP_004399369.1 hypothetical protein -
QX56_RS10965 2216893..2217399 - 507 WP_004399486.1 hypothetical protein -
QX56_RS10970 2217727..2218959 - 1233 WP_004399445.1 hypothetical protein -
QX56_RS10975 2219041..2219229 - 189 WP_004399547.1 hypothetical protein -
QX56_RS21765 2219274..2219525 - 252 WP_010886546.1 hypothetical protein Toxin
- 2219503..2219603 + 101 - - Antitoxin
QX56_RS21770 2219544..2219720 - 177 WP_009967515.1 hypothetical protein -
- 2219661..2219761 + 101 NuclAT_2 - -
- 2219661..2219761 + 101 NuclAT_2 - -
- 2219661..2219761 + 101 NuclAT_2 - -
- 2219661..2219761 + 101 NuclAT_2 - -
QX56_RS10980 2220095..2220706 - 612 WP_009967516.1 lipoprotein -
QX56_RS10985 2220821..2221147 - 327 WP_009967517.1 helix-turn-helix domain-containing protein -
QX56_RS10990 2222100..2222294 + 195 WP_004399291.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2151386..2286168 134782


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(9-243)


Sequences


Toxin        


Download         Length: 84 a.a.        Molecular weight: 9956.96 Da        Isoelectric Point: 9.7930

>T50305 WP_010886546.1 NZ_CP010053:c2219525-2219274 [Bacillus subtilis]
MNFSFSSYPYYNMIKHIANMKRFSLWFTHITFIGLFLMFQLIKDYFSSEGQALINTIFVVTCIIAILLWIIYCVFLKLRN
KSH

Download         Length: 252 bp

>T50305 NZ_CP010053:c2219525-2219274 [Bacillus subtilis]
ATGAACTTCTCCTTTAGTTCCTACCCATATTATAACATGATCAAGCACATTGCAAACATGAAACGATTCTCATTATGGTT
TACCCATATCACATTCATTGGCTTATTCTTAATGTTTCAACTCATCAAAGATTACTTCAGCAGCGAAGGACAGGCGCTAA
TCAACACAATTTTTGTTGTCACATGTATCATTGCCATATTGTTATGGATCATCTATTGTGTATTCCTTAAACTAAGAAAC
AAGTCACACTAA

Antitoxin


Download         Length: 101 bp

>AT50305 NZ_CP010053:2219503-2219603 [Bacillus subtilis]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCGGCGTATACGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB C0H439


Antitoxin

Download structure file

References