Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) yonT-as-bsrG/-
Location 2199399..2199616 Replicon chromosome
Accession NZ_CP015004
Organism Bacillus subtilis strain SZMC 6179J isolate B23

Toxin (Protein)


Gene name yonT Uniprot ID O31941
Locus tag A3772_RS11405 Protein ID WP_009967515.1
Coordinates 2199399..2199575 (-) Length 59 a.a.

Antitoxin (RNA)


Gene name as-bsrG
Locus tag -
Coordinates 2199516..2199616 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A3772_RS11380 2194587..2194814 - 228 WP_004399298.1 helix-turn-helix transcriptional regulator -
A3772_RS11385 2195075..2196391 - 1317 Protein_2161 hypothetical protein -
A3772_RS11390 2196748..2197254 - 507 WP_004399486.1 hypothetical protein -
A3772_RS11395 2197582..2198814 - 1233 WP_004399445.1 hypothetical protein -
A3772_RS11400 2198896..2199084 - 189 WP_004399547.1 hypothetical protein -
A3772_RS22260 2199129..2199380 - 252 WP_010886546.1 hypothetical protein -
A3772_RS11405 2199399..2199575 - 177 WP_009967515.1 hypothetical protein Toxin
- 2199516..2199616 + 101 NuclAT_2 - Antitoxin
- 2199516..2199616 + 101 NuclAT_2 - Antitoxin
- 2199516..2199616 + 101 NuclAT_2 - Antitoxin
- 2199516..2199616 + 101 NuclAT_2 - Antitoxin
A3772_RS11410 2199950..2200561 - 612 WP_009967516.1 lipoprotein -
A3772_RS11415 2200676..2201002 - 327 WP_009967517.1 helix-turn-helix domain-containing protein -
A3772_RS11420 2201955..2202149 + 195 WP_004399291.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2131241..2266023 134782


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(4-44)


Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6882.45 Da        Isoelectric Point: 12.8833

>T62010 WP_009967515.1 NZ_CP015004:c2199575-2199399 [Bacillus subtilis]
VLEKMGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Download         Length: 177 bp

>T62010 NZ_CP015004:c2199575-2199399 [Bacillus subtilis]
GTGCTTGAGAAAATGGGTATCGTAGTTGCTTTCCTCATATCTTTAACGGTTCTTACAATCAACAGTCTAACAATAGTTGA
GAAGGTAAGAAACCTAAAGAATGGGACAAGCAAAAAGAAAAAGCGTATACGCAAGCGGCTCCGACCAAAGAGACAACGCC
AACGTATACGCCGATGA

Antitoxin


Download         Length: 101 bp

>AT62010 NZ_CP015004:2199516-2199616 [Bacillus subtilis]
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTACGATACCCATTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB O31941

Antitoxin

Download structure file

References