Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | bsrG-as-bsrH/- |
Location | 2291606..2291896 | Replicon | chromosome |
Accession | NZ_LN680001 | ||
Organism | Bacillus subtilis strain BS34A |
Toxin (Protein)
Gene name | bsrG | Uniprot ID | L8EAY0 |
Locus tag | VV28_RS22435 | Protein ID | WP_009967548.1 |
Coordinates | 2291606..2291722 (+) | Length | 39 a.a. |
Antitoxin (RNA)
Gene name | as-bsrH | ||
Locus tag | - | ||
Coordinates | 2291717..2291896 (-) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
VV28_RS11260 | 2287533..2287703 | - | 171 | WP_009967544.1 | bacteriocin sublancin-168 | - |
VV28_RS11265 | 2288000..2288317 | - | 318 | WP_009967545.1 | sublancin immunity protein SunI | - |
VV28_RS11270 | 2288419..2289669 | - | 1251 | WP_004398504.1 | UV-damage repair protein uvrX | - |
VV28_RS11275 | 2289662..2289994 | - | 333 | WP_004398710.1 | YolD-like family protein | - |
VV28_RS11280 | 2290168..2290503 | + | 336 | WP_004399073.1 | hypothetical protein | - |
VV28_RS11285 | 2290546..2290902 | - | 357 | WP_004398595.1 | hypothetical protein | - |
VV28_RS11290 | 2290908..2291375 | - | 468 | WP_003246138.1 | YolA family protein | - |
VV28_RS22435 | 2291606..2291722 | + | 117 | WP_009967548.1 | type I toxin-antitoxin system toxin BsrG | Toxin |
- | 2291717..2291896 | - | 180 | NuclAT_1 | - | Antitoxin |
- | 2291717..2291896 | - | 180 | NuclAT_1 | - | Antitoxin |
- | 2291717..2291896 | - | 180 | NuclAT_1 | - | Antitoxin |
- | 2291717..2291896 | - | 180 | NuclAT_1 | - | Antitoxin |
VV28_RS11295 | 2292001..2292534 | - | 534 | WP_004399156.1 | GNAT family N-acetyltransferase | - |
VV28_RS11300 | 2292570..2293148 | - | 579 | WP_004399123.1 | SMI1/KNR4 family protein | - |
VV28_RS11305 | 2293212..2293709 | - | 498 | WP_003246188.1 | SMI1/KNR4 family protein | - |
VV28_RS11310 | 2293718..2295433 | - | 1716 | WP_004398855.1 | ribonuclease YeeF family protein | - |
VV28_RS11315 | 2295533..2296090 | - | 558 | WP_003246042.1 | SMI1/KNR4 family protein | - |
VV28_RS21760 | 2296174..2296359 | + | 186 | WP_003245951.1 | transposase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
inside | Prophage | - | - | 2169640..2305065 | 135425 | ||
inside | Prophage | - | - | 2169640..2304420 | 134780 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 39 a.a. Molecular weight: 4336.39 Da Isoelectric Point: 10.1022
>T285534 WP_009967548.1 NZ_LN680001:2291606-2291722 [Bacillus subtilis]
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK
Download Length: 117 bp
Antitoxin
Download Length: 180 bp
>AT285534 NZ_LN680001:c2291896-2291717 [Bacillus subtilis]
AATGATACAATTATATAATTATTTTTTGCATTTTGTTTAATTAAATGCATAAAATAAAAAGACCAGGGTGTTGGTAGCAC
CCTGGCTCTGTACAAAAGCTGCCCATCAAAGGGCTTGCTCGTTGTCAAATCTGCGTAGGCCTAACCCTTCAGGTGTCCAA
ACTCAAGGGAAGGTCTATTT
AATGATACAATTATATAATTATTTTTTGCATTTTGTTTAATTAAATGCATAAAATAAAAAGACCAGGGTGTTGGTAGCAC
CCTGGCTCTGTACAAAAGCTGCCCATCAAAGGGCTTGCTCGTTGTCAAATCTGCGTAGGCCTAACCCTTCAGGTGTCCAA
ACTCAAGGGAAGGTCTATTT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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