53438

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) yonT-as-bsrG/-
Location 2219790..2220007 Replicon chromosome
Accession NZ_CP011115
Organism Bacillus subtilis KCTC 1028 = ATCC 6051a strain KCTC 1028

Toxin (Protein)


Gene name yonT Uniprot ID O31941
Locus tag O7A_RS22755 Protein ID WP_009967515.1
Coordinates 2219790..2219966 (-) Length 59 a.a.

Antitoxin (RNA)


Gene name as-bsrG
Locus tag -
Coordinates 2219907..2220007 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O7A_RS11505 2214978..2215205 - 228 WP_004399298.1 helix-turn-helix transcriptional regulator -
O7A_RS11510 2215466..2216782 - 1317 WP_004399369.1 hypothetical protein -
O7A_RS11515 2217139..2217645 - 507 WP_004399486.1 hypothetical protein -
O7A_RS11520 2217973..2219205 - 1233 WP_004399445.1 hypothetical protein -
O7A_RS11525 2219287..2219475 - 189 WP_004399547.1 hypothetical protein -
O7A_RS22750 2219520..2219771 - 252 WP_010886546.1 hypothetical protein -
O7A_RS22755 2219790..2219966 - 177 WP_009967515.1 hypothetical protein Toxin
- 2219907..2220007 + 101 NuclAT_2 - Antitoxin
- 2219907..2220007 + 101 NuclAT_2 - Antitoxin
- 2219907..2220007 + 101 NuclAT_2 - Antitoxin
- 2219907..2220007 + 101 NuclAT_2 - Antitoxin
O7A_RS11535 2220341..2220952 - 612 WP_009967516.1 lipoprotein -
O7A_RS11540 2221067..2221393 - 327 WP_009967517.1 helix-turn-helix domain-containing protein -
O7A_RS11545 2222346..2222540 + 195 WP_004399291.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2151632..2286414 134782


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)


Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6882.45 Da        Isoelectric Point: 12.8833

>T53438 WP_009967515.1 NZ_CP011115:c2219966-2219790 [Bacillus subtilis KCTC 1028 = ATCC 6051a]
VLEKMGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Download         Length: 177 bp

>T53438 NZ_CP011115:c2219966-2219790 [Bacillus subtilis KCTC 1028 = ATCC 6051a]
GTGCTTGAGAAAATGGGTATCGTAGTTGCTTTCCTCATATCTTTAACGGTTCTTACAATCAACAGTCTAACAATAGTTGA
GAAGGTAAGAAACCTAAAGAATGGGACAAGCAAAAAGAAAAAGCGTATACGCAAGCGGCTCCGACCAAAGAGACAACGCC
AACGTATACGCCGATGA

Antitoxin


Download         Length: 101 bp

>AT53438 NZ_CP011115:2219907-2220007 [Bacillus subtilis KCTC 1028 = ATCC 6051a]
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTACGATACCCATTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB O31941

Antitoxin

Download structure file

References