Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) yonT-SR6/-
Location 2212733..2213062 Replicon chromosome
Accession NZ_CP125762
Organism Bacillus subtilis strain KRS015

Toxin (Protein)


Gene name yonT Uniprot ID C0H439
Locus tag QLQ05_RS12195 Protein ID WP_010886546.1
Coordinates 2212811..2213062 (+) Length 84 a.a.

Antitoxin (RNA)


Gene name SR6
Locus tag -
Coordinates 2212733..2212833 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QLQ05_RS12175 2210042..2210236 - 195 WP_004399291.1 hypothetical protein -
QLQ05_RS12180 2211189..2211515 + 327 WP_009967517.1 helix-turn-helix transcriptional regulator -
QLQ05_RS12185 2211630..2212241 + 612 WP_009967516.1 lipoprotein -
- 2212575..2212675 - 101 NuclAT_4 - -
- 2212575..2212675 - 101 NuclAT_4 - -
- 2212575..2212675 - 101 NuclAT_4 - -
- 2212575..2212675 - 101 NuclAT_4 - -
QLQ05_RS12190 2212616..2212792 + 177 WP_009967515.1 hypothetical protein -
- 2212733..2212833 - 101 - - Antitoxin
QLQ05_RS12195 2212811..2213062 + 252 WP_010886546.1 hypothetical protein Toxin
QLQ05_RS12200 2213107..2213295 + 189 WP_004399547.1 hypothetical protein -
QLQ05_RS12205 2213377..2214609 + 1233 WP_004399445.1 hypothetical protein -
QLQ05_RS12210 2214937..2215443 + 507 WP_004399486.1 hypothetical protein -
QLQ05_RS12215 2215800..2217116 + 1317 WP_004399369.1 hypothetical protein -
QLQ05_RS12220 2217377..2217604 + 228 WP_004399298.1 helix-turn-helix transcriptional regulator -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2012030..2280951 268921


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 84 a.a.        Molecular weight: 9956.96 Da        Isoelectric Point: 9.7930

>T282380 WP_010886546.1 NZ_CP125762:2212811-2213062 [Bacillus subtilis]
MNFSFSSYPYYNMIKHIANMKRFSLWFTHITFIGLFLMFQLIKDYFSSEGQALINTIFVVTCIIAILLWIIYCVFLKLRN
KSH

Download         Length: 252 bp

>T282380 NZ_CP125762:2212811-2213062 [Bacillus subtilis]
ATGAACTTCTCCTTTAGTTCCTACCCATATTATAACATGATCAAGCACATTGCAAACATGAAACGATTCTCATTATGGTT
TACCCATATCACATTCATTGGCTTATTCTTAATGTTTCAACTCATCAAAGATTACTTCAGCAGCGAAGGACAGGCGCTAA
TCAACACAATTTTTGTTGTCACATGTATCATTGCCATATTGTTATGGATCATCTATTGTGTATTCCTTAAACTAAGAAAC
AAGTCACACTAA

Antitoxin


Download         Length: 101 bp

>AT282380 NZ_CP125762:c2212833-2212733 [Bacillus subtilis]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCGGCGTATACGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB C0H439


Antitoxin

Download structure file

References