Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) yonT-as-bsrG/-
Location 2191562..2191779 Replicon chromosome
Accession NZ_AP024628
Organism Bacillus subtilis strain BEST3145

Toxin (Protein)


Gene name yonT Uniprot ID O31941
Locus tag K6K00_RS11180 Protein ID WP_009967515.1
Coordinates 2191562..2191738 (-) Length 59 a.a.

Antitoxin (RNA)


Gene name as-bsrG
Locus tag -
Coordinates 2191679..2191779 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6K00_RS11150 (2186750) 2186750..2186977 - 228 WP_004399298.1 helix-turn-helix transcriptional regulator -
K6K00_RS11155 (2187238) 2187238..2188554 - 1317 WP_004399369.1 hypothetical protein -
K6K00_RS11160 (2188911) 2188911..2189417 - 507 WP_004399486.1 hypothetical protein -
K6K00_RS11165 (2189745) 2189745..2190977 - 1233 WP_004399445.1 hypothetical protein -
K6K00_RS11170 (2191059) 2191059..2191247 - 189 WP_004399547.1 hypothetical protein -
K6K00_RS11175 (2191292) 2191292..2191543 - 252 WP_010886546.1 hypothetical protein -
K6K00_RS11180 (2191562) 2191562..2191738 - 177 WP_009967515.1 hypothetical protein Toxin
- (2191679) 2191679..2191779 + 101 NuclAT_2 - Antitoxin
- (2191679) 2191679..2191779 + 101 NuclAT_2 - Antitoxin
- (2191679) 2191679..2191779 + 101 NuclAT_2 - Antitoxin
- (2191679) 2191679..2191779 + 101 NuclAT_2 - Antitoxin
K6K00_RS11185 (2192113) 2192113..2192724 - 612 WP_009967516.1 lipoprotein -
K6K00_RS11190 (2192839) 2192839..2193165 - 327 WP_009967517.1 helix-turn-helix transcriptional regulator -
K6K00_RS11195 (2194118) 2194118..2194312 + 195 WP_004399291.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2123406..2258186 134780


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6882.45 Da        Isoelectric Point: 12.8833

>T39133 WP_009967515.1 NZ_AP024628:c2191738-2191562 [Bacillus subtilis]
VLEKMGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Download         Length: 177 bp

>T39133 NZ_AP024628:c2191738-2191562 [Bacillus subtilis]
GTGCTTGAGAAAATGGGTATCGTAGTTGCTTTCCTCATATCTTTAACGGTTCTTACAATCAACAGTCTAACAATAGTTGA
GAAGGTAAGAAACCTAAAGAATGGGACAAGCAAAAAGAAAAAGCGTATACGCAAGCGGCTCCGACCAAAGAGACAACGCC
AACGTATACGCCGATGA

Antitoxin


Download         Length: 101 bp

>AT39133 NZ_AP024628:2191679-2191779 [Bacillus subtilis]
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTACGATACCCATTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB O31941

Antitoxin

Download structure file

References