Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) yonT-as-bsrG/-
Location 2219816..2220033 Replicon chromosome
Accession NZ_CP020102
Organism Bacillus subtilis strain NCIB 3610

Toxin (Protein)


Gene name yonT Uniprot ID O31941
Locus tag B4U62_RS11430 Protein ID WP_009967515.1
Coordinates 2219816..2219992 (-) Length 59 a.a.

Antitoxin (RNA)


Gene name as-bsrG
Locus tag -
Coordinates 2219933..2220033 (+)

Genomic Context

-----B4U62_RS11445B4U62_RS11400B4U62_RS11405B4U62_RS11410B4U62_RS11415B4U62_RS11420B4U62_RS11425B4U62_RS11430B4U62_RS11435B4U62_RS11440
Location: 2219933..2220033 (101 bp)
Type: Antitoxin
Protein ID: NuclAT_2
Location: 2219933..2220033 (101 bp)
Type: Antitoxin
Protein ID: NuclAT_2
Location: 2219933..2220033 (101 bp)
Type: Antitoxin
Protein ID: NuclAT_2
Location: 2219933..2220033 (101 bp)
Type: Antitoxin
Protein ID: NuclAT_2
Location: 2222372..2222566 (195 bp)
Type: Others
Protein ID: WP_004399291.1
Location: 2215004..2215231 (228 bp)
Type: Others
Protein ID: WP_004399298.1
Location: 2215492..2216808 (1317 bp)
Type: Others
Protein ID: WP_004399369.1
Location: 2217165..2217671 (507 bp)
Type: Others
Protein ID: WP_004399486.1
Location: 2217999..2219231 (1233 bp)
Type: Others
Protein ID: WP_004399445.1
Location: 2219313..2219501 (189 bp)
Type: Others
Protein ID: WP_004399547.1
Location: 2219546..2219797 (252 bp)
Type: Others
Protein ID: WP_010886546.1
Location: 2219816..2219992 (177 bp)
Type: Toxin
Protein ID: WP_009967515.1
Location: 2220367..2220978 (612 bp)
Type: Others
Protein ID: WP_009967516.1
Location: 2221093..2221419 (327 bp)
Type: Others
Protein ID: WP_009967517.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
B4U62_RS114002215004..2215231-228WP_004399298.1helix-turn-helix transcriptional regulator-
B4U62_RS114052215492..2216808-1317WP_004399369.1hypothetical protein-
B4U62_RS114102217165..2217671-507WP_004399486.1hypothetical protein-
B4U62_RS114152217999..2219231-1233WP_004399445.1hypothetical protein-
B4U62_RS114202219313..2219501-189WP_004399547.1hypothetical protein-
B4U62_RS114252219546..2219797-252WP_010886546.1hypothetical protein-
B4U62_RS114302219816..2219992-177WP_009967515.1hypothetical proteinToxin
-2219933..2220033+101NuclAT_2-Antitoxin
-2219933..2220033+101NuclAT_2-Antitoxin
-2219933..2220033+101NuclAT_2-Antitoxin
-2219933..2220033+101NuclAT_2-Antitoxin
B4U62_RS114352220367..2220978-612WP_009967516.1lipoprotein-
B4U62_RS114402221093..2221419-327WP_009967517.1helix-turn-helix domain-containing protein-
B4U62_RS114452222372..2222566+195WP_004399291.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
insideProphage--2151659..2286440134781


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(6-99)


Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6882.45 Da        Isoelectric Point: 12.8833

>T74086 WP_009967515.1 NZ_CP020102:c2219992-2219816 [Bacillus subtilis]
VLEKMGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Download         Length: 177 bp

>T74086 NZ_CP020102:c2219992-2219816 [Bacillus subtilis]
GTGCTTGAGAAAATGGGTATCGTAGTTGCTTTCCTCATATCTTTAACGGTTCTTACAATCAACAGTCTAACAATAGTTGA
GAAGGTAAGAAACCTAAAGAATGGGACAAGCAAAAAGAAAAAGCGTATACGCAAGCGGCTCCGACCAAAGAGACAACGCC
AACGTATACGCCGATGA

Antitoxin


Download         Length: 101 bp

>AT74086 NZ_CP020102:2219933-2220033 [Bacillus subtilis]
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTACGATACCCATTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBO31941

Antitoxin

Download structure file

References