Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) yonT-as-bsrG/-
Location 2219816..2220033 Replicon chromosome
Accession NZ_CP020102
Organism Bacillus subtilis strain NCIB 3610

Toxin (Protein)


Gene name yonT Uniprot ID O31941
Locus tag B4U62_RS11430 Protein ID WP_009967515.1
Coordinates 2219816..2219992 (-) Length 59 a.a.

Antitoxin (RNA)


Gene name as-bsrG
Locus tag -
Coordinates 2219933..2220033 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B4U62_RS11400 2215004..2215231 - 228 WP_004399298.1 helix-turn-helix transcriptional regulator -
B4U62_RS11405 2215492..2216808 - 1317 WP_004399369.1 hypothetical protein -
B4U62_RS11410 2217165..2217671 - 507 WP_004399486.1 hypothetical protein -
B4U62_RS11415 2217999..2219231 - 1233 WP_004399445.1 hypothetical protein -
B4U62_RS11420 2219313..2219501 - 189 WP_004399547.1 hypothetical protein -
B4U62_RS11425 2219546..2219797 - 252 WP_010886546.1 hypothetical protein -
B4U62_RS11430 2219816..2219992 - 177 WP_009967515.1 hypothetical protein Toxin
- 2219933..2220033 + 101 NuclAT_2 - Antitoxin
- 2219933..2220033 + 101 NuclAT_2 - Antitoxin
- 2219933..2220033 + 101 NuclAT_2 - Antitoxin
- 2219933..2220033 + 101 NuclAT_2 - Antitoxin
B4U62_RS11435 2220367..2220978 - 612 WP_009967516.1 lipoprotein -
B4U62_RS11440 2221093..2221419 - 327 WP_009967517.1 helix-turn-helix domain-containing protein -
B4U62_RS11445 2222372..2222566 + 195 WP_004399291.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2151659..2286440 134781


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(6-99)


Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6882.45 Da        Isoelectric Point: 12.8833

>T74086 WP_009967515.1 NZ_CP020102:c2219992-2219816 [Bacillus subtilis]
VLEKMGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Download         Length: 177 bp

>T74086 NZ_CP020102:c2219992-2219816 [Bacillus subtilis]
GTGCTTGAGAAAATGGGTATCGTAGTTGCTTTCCTCATATCTTTAACGGTTCTTACAATCAACAGTCTAACAATAGTTGA
GAAGGTAAGAAACCTAAAGAATGGGACAAGCAAAAAGAAAAAGCGTATACGCAAGCGGCTCCGACCAAAGAGACAACGCC
AACGTATACGCCGATGA

Antitoxin


Download         Length: 101 bp

>AT74086 NZ_CP020102:2219933-2220033 [Bacillus subtilis]
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTACGATACCCATTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB O31941

Antitoxin

Download structure file

References