Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) yonT-as-bsrG/-
Location 2219125..2219612 Replicon chromosome
Accession NZ_CP125660
Organism Bacillus subtilis strain GUCC48

Toxin (Protein)


Gene name yonT Uniprot ID C0H439
Locus tag QLH41_RS11440 Protein ID WP_010886546.1
Coordinates 2219125..2219376 (-) Length 84 a.a.

Antitoxin (RNA)


Gene name as-bsrG
Locus tag -
Coordinates 2219512..2219612 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QLH41_RS11415 (2214583) 2214583..2214810 - 228 WP_004399298.1 helix-turn-helix transcriptional regulator -
QLH41_RS11420 (2215071) 2215071..2216387 - 1317 WP_004399369.1 hypothetical protein -
QLH41_RS11425 (2216744) 2216744..2217250 - 507 WP_004399486.1 hypothetical protein -
QLH41_RS11430 (2217578) 2217578..2218810 - 1233 WP_004399445.1 hypothetical protein -
QLH41_RS11435 (2218892) 2218892..2219080 - 189 WP_004399547.1 hypothetical protein -
QLH41_RS11440 (2219125) 2219125..2219376 - 252 WP_010886546.1 hypothetical protein Toxin
QLH41_RS11445 (2219395) 2219395..2219571 - 177 WP_009967515.1 hypothetical protein -
- (2219512) 2219512..2219612 + 101 NuclAT_2 - Antitoxin
- (2219512) 2219512..2219612 + 101 NuclAT_2 - Antitoxin
- (2219512) 2219512..2219612 + 101 NuclAT_2 - Antitoxin
- (2219512) 2219512..2219612 + 101 NuclAT_2 - Antitoxin
QLH41_RS11450 (2219946) 2219946..2220557 - 612 WP_009967516.1 lipoprotein -
QLH41_RS11455 (2220672) 2220672..2220998 - 327 WP_009967517.1 helix-turn-helix transcriptional regulator -
QLH41_RS11460 (2221951) 2221951..2222145 + 195 WP_004399291.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2151237..2286019 134782


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9956.96 Da        Isoelectric Point: 9.7930

>T282255 WP_010886546.1 NZ_CP125660:c2219376-2219125 [Bacillus subtilis]
MNFSFSSYPYYNMIKHIANMKRFSLWFTHITFIGLFLMFQLIKDYFSSEGQALINTIFVVTCIIAILLWIIYCVFLKLRN
KSH

Download         Length: 252 bp

Antitoxin


Download         Length: 101 bp

>AT282255 NZ_CP125660:2219512-2219612 [Bacillus subtilis]
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTACGATACCCATTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB C0H439

Antitoxin

Download structure file

References