50308

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) yonT-SR6/-
Location 2219503..2219720 Replicon chromosome
Accession NZ_CP010053
Organism Bacillus subtilis strain PS832

Toxin (Protein)


Gene name yonT Uniprot ID O31941
Locus tag QX56_RS21770 Protein ID WP_009967515.1
Coordinates 2219544..2219720 (-) Length 59 a.a.

Antitoxin (RNA)


Gene name SR6
Locus tag -
Coordinates 2219503..2219603 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QX56_RS10955 2214732..2214959 - 228 WP_004399298.1 helix-turn-helix transcriptional regulator -
QX56_RS10960 2215220..2216536 - 1317 WP_004399369.1 hypothetical protein -
QX56_RS10965 2216893..2217399 - 507 WP_004399486.1 hypothetical protein -
QX56_RS10970 2217727..2218959 - 1233 WP_004399445.1 hypothetical protein -
QX56_RS10975 2219041..2219229 - 189 WP_004399547.1 hypothetical protein -
QX56_RS21765 2219274..2219525 - 252 WP_010886546.1 hypothetical protein -
- 2219503..2219603 + 101 - - Antitoxin
QX56_RS21770 2219544..2219720 - 177 WP_009967515.1 hypothetical protein Toxin
- 2219661..2219761 + 101 NuclAT_2 - -
- 2219661..2219761 + 101 NuclAT_2 - -
- 2219661..2219761 + 101 NuclAT_2 - -
- 2219661..2219761 + 101 NuclAT_2 - -
QX56_RS10980 2220095..2220706 - 612 WP_009967516.1 lipoprotein -
QX56_RS10985 2220821..2221147 - 327 WP_009967517.1 helix-turn-helix domain-containing protein -
QX56_RS10990 2222100..2222294 + 195 WP_004399291.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2151386..2286168 134782


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(4-111)


Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6882.45 Da        Isoelectric Point: 12.8833

>T50308 WP_009967515.1 NZ_CP010053:c2219720-2219544 [Bacillus subtilis]
VLEKMGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Download         Length: 177 bp

>T50308 NZ_CP010053:c2219720-2219544 [Bacillus subtilis]
GTGCTTGAGAAAATGGGTATCGTAGTTGCTTTCCTCATATCTTTAACGGTTCTTACAATCAACAGTCTAACAATAGTTGA
GAAGGTAAGAAACCTAAAGAATGGGACAAGCAAAAAGAAAAAGCGTATACGCAAGCGGCTCCGACCAAAGAGACAACGCC
AACGTATACGCCGATGA

Antitoxin


Download         Length: 101 bp

>AT50308 NZ_CP010053:2219503-2219603 [Bacillus subtilis]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCGGCGTATACGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB O31941

Antitoxin

Download structure file

References