Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) yonT-SR6/-
Location 2219335..2219552 Replicon chromosome
Accession NZ_CP045922
Organism Bacillus subtilis strain P8_B1

Toxin (Protein)


Gene name yonT Uniprot ID O31941
Locus tag GII87_RS11420 Protein ID WP_009967515.1
Coordinates 2219376..2219552 (-) Length 59 a.a.

Antitoxin (RNA)


Gene name SR6
Locus tag -
Coordinates 2219335..2219435 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GII87_RS11390 2214564..2214791 - 228 WP_004399298.1 helix-turn-helix transcriptional regulator -
GII87_RS11395 2215052..2216368 - 1317 WP_004399369.1 hypothetical protein -
GII87_RS11400 2216725..2217231 - 507 WP_004399486.1 hypothetical protein -
GII87_RS11405 2217559..2218791 - 1233 WP_004399445.1 hypothetical protein -
GII87_RS11410 2218873..2219061 - 189 WP_004399547.1 hypothetical protein -
GII87_RS11415 2219106..2219357 - 252 WP_010886546.1 hypothetical protein -
- 2219335..2219435 + 101 - - Antitoxin
GII87_RS11420 2219376..2219552 - 177 WP_009967515.1 hypothetical protein Toxin
- 2219493..2219593 + 101 NuclAT_2 - -
- 2219493..2219593 + 101 NuclAT_2 - -
- 2219493..2219593 + 101 NuclAT_2 - -
- 2219493..2219593 + 101 NuclAT_2 - -
GII87_RS11425 2219927..2220538 - 612 WP_009967516.1 lipoprotein -
GII87_RS11430 2220653..2220979 - 327 WP_009967517.1 helix-turn-helix domain-containing protein -
GII87_RS11435 2221932..2222126 + 195 WP_004399291.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2151218..2286000 134782


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6882.45 Da        Isoelectric Point: 12.8833

>T143010 WP_009967515.1 NZ_CP045922:c2219552-2219376 [Bacillus subtilis]
VLEKMGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Download         Length: 177 bp

>T143010 NZ_CP060924:2676280-2676387 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGGATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 101 bp

>AT143010 NZ_CP045922:2219335-2219435 [Bacillus subtilis]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCGGCGTATACGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB O31941

Antitoxin

Download structure file

References