Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) yonT-SR6/-
Location 2219335..2219552 Replicon chromosome
Accession NZ_CP045922
Organism Bacillus subtilis strain P8_B1

Toxin (Protein)


Gene name yonT Uniprot ID O31941
Locus tag GII87_RS11420 Protein ID WP_009967515.1
Coordinates 2219376..2219552 (-) Length 59 a.a.

Antitoxin (RNA)


Gene name SR6
Locus tag -
Coordinates 2219335..2219435 (+)

Genomic Context

------GII87_RS11435GII87_RS11390GII87_RS11395GII87_RS11400GII87_RS11405GII87_RS11410GII87_RS11415GII87_RS11420GII87_RS11425GII87_RS11430
Location: 2219335..2219435 (101 bp)
Type: Antitoxin
Protein ID: -
Location: 2219493..2219593 (101 bp)
Type: Others
Protein ID: NuclAT_2
Location: 2219493..2219593 (101 bp)
Type: Others
Protein ID: NuclAT_2
Location: 2219493..2219593 (101 bp)
Type: Others
Protein ID: NuclAT_2
Location: 2219493..2219593 (101 bp)
Type: Others
Protein ID: NuclAT_2
Location: 2221932..2222126 (195 bp)
Type: Others
Protein ID: WP_004399291.1
Location: 2214564..2214791 (228 bp)
Type: Others
Protein ID: WP_004399298.1
Location: 2215052..2216368 (1317 bp)
Type: Others
Protein ID: WP_004399369.1
Location: 2216725..2217231 (507 bp)
Type: Others
Protein ID: WP_004399486.1
Location: 2217559..2218791 (1233 bp)
Type: Others
Protein ID: WP_004399445.1
Location: 2218873..2219061 (189 bp)
Type: Others
Protein ID: WP_004399547.1
Location: 2219106..2219357 (252 bp)
Type: Others
Protein ID: WP_010886546.1
Location: 2219376..2219552 (177 bp)
Type: Toxin
Protein ID: WP_009967515.1
Location: 2219927..2220538 (612 bp)
Type: Others
Protein ID: WP_009967516.1
Location: 2220653..2220979 (327 bp)
Type: Others
Protein ID: WP_009967517.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
GII87_RS113902214564..2214791-228WP_004399298.1helix-turn-helix transcriptional regulator-
GII87_RS113952215052..2216368-1317WP_004399369.1hypothetical protein-
GII87_RS114002216725..2217231-507WP_004399486.1hypothetical protein-
GII87_RS114052217559..2218791-1233WP_004399445.1hypothetical protein-
GII87_RS114102218873..2219061-189WP_004399547.1hypothetical protein-
GII87_RS114152219106..2219357-252WP_010886546.1hypothetical protein-
-2219335..2219435+101--Antitoxin
GII87_RS114202219376..2219552-177WP_009967515.1hypothetical proteinToxin
-2219493..2219593+101NuclAT_2--
-2219493..2219593+101NuclAT_2--
-2219493..2219593+101NuclAT_2--
-2219493..2219593+101NuclAT_2--
GII87_RS114252219927..2220538-612WP_009967516.1lipoprotein-
GII87_RS114302220653..2220979-327WP_009967517.1helix-turn-helix domain-containing protein-
GII87_RS114352221932..2222126+195WP_004399291.1hypothetical protein-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
insideProphage--2151218..2286000134782


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6882.45 Da        Isoelectric Point: 12.8833

>T143010 WP_009967515.1 NZ_CP045922:c2219552-2219376 [Bacillus subtilis]
VLEKMGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Download         Length: 177 bp

>T143010 NZ_CP060924:2676280-2676387 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGGATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 101 bp

>AT143010 NZ_CP045922:2219335-2219435 [Bacillus subtilis]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCGGCGTATACGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
AlphaFold DBO31941

Antitoxin

Download structure file

References