Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) yonT-SR6/-
Location 2219340..2219557 Replicon chromosome
Accession NZ_CP082924
Organism Bacillus subtilis strain FJAT-4

Toxin (Protein)


Gene name yonT Uniprot ID O31941
Locus tag K8U58_RS11435 Protein ID WP_009967515.1
Coordinates 2219381..2219557 (-) Length 59 a.a.

Antitoxin (RNA)


Gene name SR6
Locus tag -
Coordinates 2219340..2219440 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K8U58_RS11405 2214569..2214796 - 228 WP_004399298.1 helix-turn-helix transcriptional regulator -
K8U58_RS11410 2215057..2216373 - 1317 WP_004399369.1 hypothetical protein -
K8U58_RS11415 2216730..2217236 - 507 WP_004399486.1 hypothetical protein -
K8U58_RS11420 2217564..2218796 - 1233 WP_004399445.1 hypothetical protein -
K8U58_RS11425 2218878..2219066 - 189 WP_004399547.1 hypothetical protein -
K8U58_RS11430 2219111..2219362 - 252 WP_010886546.1 hypothetical protein -
- 2219340..2219440 + 101 - - Antitoxin
K8U58_RS11435 2219381..2219557 - 177 WP_009967515.1 hypothetical protein Toxin
- 2219498..2219598 + 101 NuclAT_2 - -
- 2219498..2219598 + 101 NuclAT_2 - -
- 2219498..2219598 + 101 NuclAT_2 - -
- 2219498..2219598 + 101 NuclAT_2 - -
K8U58_RS11440 2219932..2220543 - 612 WP_009967516.1 lipoprotein -
K8U58_RS11445 2220658..2220984 - 327 WP_009967517.1 helix-turn-helix transcriptional regulator -
K8U58_RS11450 2221937..2222131 + 195 WP_004399291.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2151226..2286650 135424


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6882.45 Da        Isoelectric Point: 12.8833

>T215602 WP_009967515.1 NZ_CP082924:c2219557-2219381 [Bacillus subtilis]
VLEKMGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Download         Length: 177 bp

>T215602 NZ_CP110823:c3728504-3728181 [Enterobacter roggenkampii]
ATGAAATATCAACCTGCAACAACCCTCTGGGCAGCGAAGCCAAGCCTGTCGCCCGTGGCTGTCTGGCAAATGCTACTTAC
ACGGCTGCTGGAACAGCATTATGGTCTGACGCTAAACGATACTCCTTTCTGTGATGAAACCGTTATACAGGAACATATCG
ATGCCGGTATCACTCTGGCTAATGCCGTTAACTTTCTGGTGGAAAAGTACGAACTGGCCCGTATCGATCACAGAGGGTTT
GGCTGGAACGAACAAACACCATATCTCACAATCGTTGATATTATGAGGGCCCGCCGCGATCTTGGTTTATTGAATCGTAA
TTAG

Antitoxin


Download         Length: 101 bp

>AT215602 NZ_CP082924:2219340-2219440 [Bacillus subtilis]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCGGCGTATACGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB O31941

Antitoxin

Download structure file

References