Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) bsrG-as-bsrH/-
Location 2273186..2273476 Replicon chromosome
Accession NZ_CP045812
Organism Bacillus subtilis strain P8_B3

Toxin (Protein)


Gene name bsrG Uniprot ID L8EAY0
Locus tag GII89_RS11700 Protein ID WP_009967548.1
Coordinates 2273186..2273302 (+) Length 39 a.a.

Antitoxin (RNA)


Gene name as-bsrH
Locus tag -
Coordinates 2273297..2273476 (-)

Genomic Context

GII89_RS11685GII89_RS11700GII89_RS11730GII89_RS11665GII89_RS11670GII89_RS11675GII89_RS11680GII89_RS11690GII89_RS11695-----GII89_RS11705GII89_RS11710GII89_RS11715GII89_RS11720GII89_RS11725
Location: 2271748..2272083 (336 bp)
Type: Others
Protein ID: WP_004399073.1
Location: 2273186..2273302 (117 bp)
Type: Toxin
Protein ID: WP_009967548.1
Location: 2277739..2277939 (201 bp)
Type: Others
Protein ID: WP_161793078.1
Location: 2269113..2269283 (171 bp)
Type: Others
Protein ID: WP_009967544.1
Location: 2269580..2269897 (318 bp)
Type: Others
Protein ID: WP_009967545.1
Location: 2269999..2271249 (1251 bp)
Type: Others
Protein ID: WP_004398504.1
Location: 2271242..2271574 (333 bp)
Type: Others
Protein ID: WP_004398710.1
Location: 2272126..2272482 (357 bp)
Type: Others
Protein ID: WP_004398595.1
Location: 2272488..2272955 (468 bp)
Type: Others
Protein ID: WP_003246138.1
Location: 2273297..2273476 (180 bp)
Type: Antitoxin
Protein ID: NuclAT_1
Location: 2273297..2273476 (180 bp)
Type: Antitoxin
Protein ID: NuclAT_1
Location: 2273297..2273476 (180 bp)
Type: Antitoxin
Protein ID: NuclAT_1
Location: 2273297..2273476 (180 bp)
Type: Antitoxin
Protein ID: NuclAT_1
Location: 2273581..2274114 (534 bp)
Type: Others
Protein ID: WP_004399156.1
Location: 2274150..2274728 (579 bp)
Type: Others
Protein ID: WP_004399123.1
Location: 2274792..2275289 (498 bp)
Type: Others
Protein ID: WP_003246188.1
Location: 2275298..2277013 (1716 bp)
Type: Others
Protein ID: WP_004398855.1
Location: 2277113..2277670 (558 bp)
Type: Others
Protein ID: WP_003246042.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
GII89_RS116652269113..2269283-171WP_009967544.1bacteriocin sublancin-168-
GII89_RS116702269580..2269897-318WP_009967545.1sublancin immunity protein SunI-
GII89_RS116752269999..2271249-1251WP_004398504.1UV-damage repair protein uvrX-
GII89_RS116802271242..2271574-333WP_004398710.1YolD-like family protein-
GII89_RS116852271748..2272083+336WP_004399073.1hypothetical protein-
GII89_RS116902272126..2272482-357WP_004398595.1hypothetical protein-
GII89_RS116952272488..2272955-468WP_003246138.1YolA family protein-
GII89_RS117002273186..2273302+117WP_009967548.1type I toxin-antitoxin system toxin BsrGToxin
-2273297..2273476-180NuclAT_1-Antitoxin
-2273297..2273476-180NuclAT_1-Antitoxin
-2273297..2273476-180NuclAT_1-Antitoxin
-2273297..2273476-180NuclAT_1-Antitoxin
GII89_RS117052273581..2274114-534WP_004399156.1GNAT family N-acetyltransferase-
GII89_RS117102274150..2274728-579WP_004399123.1SMI1/KNR4 family protein-
GII89_RS117152274792..2275289-498WP_003246188.1SMI1/KNR4 family protein-
GII89_RS117202275298..2277013-1716WP_004398855.1ribonuclease YeeF family protein-
GII89_RS117252277113..2277670-558WP_003246042.1SMI1/KNR4 family protein-
GII89_RS117302277739..2277939+201WP_161793078.1transposase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
insideProphage--2151218..2286000134782


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(1-38)


Sequences

Toxin        


Download         Length: 39 a.a.        Molecular weight: 4336.39 Da        Isoelectric Point: 10.1022

>T142644 WP_009967548.1 NZ_CP045812:2273186-2273302 [Bacillus subtilis]
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK

Download         Length: 117 bp

>T142644 NZ_CP060807:337595-337963 [Klebsiella variicola]
ATGACGCTGCAGATTATCTCAGCGGAAGAGATAATACAGTTTCACGACAGGCTGCTCCGCGTCACGCCTGACGTTGCCGG
TATGCCCGACCCGGGGCGTGCCGAAGCGATAATGTATAGGGTGCTAAACAAAATTGAATATGAAGGTGTGACAGACGTGT
GGCGACTCGCTGCGATGCACCTGCTGGTGATTTCTCGCGGCCATATTTTCAATGATGGAAATAAGCGTACGGCACTGTTT
ATTACCCTGCTTTTTTTAAAGCGAAATGGAATTATATTGCCGGCGAATCCGGACTTCGTCGGCATGACCGTCGAGGCGGC
AGCGGGGCAACTTACCCTGGAACAGATTGTCGCGCGTTTGCGCGGATGA

Antitoxin


Download         Length: 180 bp

>AT142644 NZ_CP045812:c2273476-2273297 [Bacillus subtilis]
AATGATACAATTATATAATTATTTTTTGCATTTTGTTTAATTAAATGCATAAAATAAAAAGACCAGGGTGTTGGTAGCAC
CCTGGCTCTGTACAAAAGCTGCCCATCAAAGGGCTTGCTCGTTGTCAAATCTGCGTAGGCCTAACCCTTCAGGTGTCCAA
ACTCAAGGGAAGGTCTATTT

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A7Z7EVU9

Antitoxin

Download structure file

References