142644

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) bsrG-as-bsrH/-
Location 2273186..2273476 Replicon chromosome
Accession NZ_CP045812
Organism Bacillus subtilis strain P8_B3

Toxin (Protein)


Gene name bsrG Uniprot ID L8EAY0
Locus tag GII89_RS11700 Protein ID WP_009967548.1
Coordinates 2273186..2273302 (+) Length 39 a.a.

Antitoxin (RNA)


Gene name as-bsrH
Locus tag -
Coordinates 2273297..2273476 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GII89_RS11665 2269113..2269283 - 171 WP_009967544.1 bacteriocin sublancin-168 -
GII89_RS11670 2269580..2269897 - 318 WP_009967545.1 sublancin immunity protein SunI -
GII89_RS11675 2269999..2271249 - 1251 WP_004398504.1 UV-damage repair protein uvrX -
GII89_RS11680 2271242..2271574 - 333 WP_004398710.1 YolD-like family protein -
GII89_RS11685 2271748..2272083 + 336 WP_004399073.1 hypothetical protein -
GII89_RS11690 2272126..2272482 - 357 WP_004398595.1 hypothetical protein -
GII89_RS11695 2272488..2272955 - 468 WP_003246138.1 YolA family protein -
GII89_RS11700 2273186..2273302 + 117 WP_009967548.1 type I toxin-antitoxin system toxin BsrG Toxin
- 2273297..2273476 - 180 NuclAT_1 - Antitoxin
- 2273297..2273476 - 180 NuclAT_1 - Antitoxin
- 2273297..2273476 - 180 NuclAT_1 - Antitoxin
- 2273297..2273476 - 180 NuclAT_1 - Antitoxin
GII89_RS11705 2273581..2274114 - 534 WP_004399156.1 GNAT family N-acetyltransferase -
GII89_RS11710 2274150..2274728 - 579 WP_004399123.1 SMI1/KNR4 family protein -
GII89_RS11715 2274792..2275289 - 498 WP_003246188.1 SMI1/KNR4 family protein -
GII89_RS11720 2275298..2277013 - 1716 WP_004398855.1 ribonuclease YeeF family protein -
GII89_RS11725 2277113..2277670 - 558 WP_003246042.1 SMI1/KNR4 family protein -
GII89_RS11730 2277739..2277939 + 201 WP_161793078.1 transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2151218..2286000 134782


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(1-38)


Sequences

Toxin        


Download         Length: 39 a.a.        Molecular weight: 4336.39 Da        Isoelectric Point: 10.1022

>T142644 WP_009967548.1 NZ_CP045812:2273186-2273302 [Bacillus subtilis]
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK

Download         Length: 117 bp

>T142644 NZ_CP060807:337595-337963 [Klebsiella variicola]
ATGACGCTGCAGATTATCTCAGCGGAAGAGATAATACAGTTTCACGACAGGCTGCTCCGCGTCACGCCTGACGTTGCCGG
TATGCCCGACCCGGGGCGTGCCGAAGCGATAATGTATAGGGTGCTAAACAAAATTGAATATGAAGGTGTGACAGACGTGT
GGCGACTCGCTGCGATGCACCTGCTGGTGATTTCTCGCGGCCATATTTTCAATGATGGAAATAAGCGTACGGCACTGTTT
ATTACCCTGCTTTTTTTAAAGCGAAATGGAATTATATTGCCGGCGAATCCGGACTTCGTCGGCATGACCGTCGAGGCGGC
AGCGGGGCAACTTACCCTGGAACAGATTGTCGCGCGTTTGCGCGGATGA

Antitoxin


Download         Length: 180 bp

>AT142644 NZ_CP045812:c2273476-2273297 [Bacillus subtilis]
AATGATACAATTATATAATTATTTTTTGCATTTTGTTTAATTAAATGCATAAAATAAAAAGACCAGGGTGTTGGTAGCAC
CCTGGCTCTGTACAAAAGCTGCCCATCAAAGGGCTTGCTCGTTGTCAAATCTGCGTAGGCCTAACCCTTCAGGTGTCCAA
ACTCAAGGGAAGGTCTATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7Z7EVU9

Antitoxin

Download structure file

References