Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) yonT-as-bsrG/-
Location 2219200..2219417 Replicon chromosome
Accession NZ_CP016852
Organism Bacillus subtilis subsp. subtilis strain 168G

Toxin (Protein)


Gene name yonT Uniprot ID O31941
Locus tag BFI33_RS11525 Protein ID WP_009967515.1
Coordinates 2219200..2219376 (-) Length 59 a.a.

Antitoxin (RNA)


Gene name as-bsrG
Locus tag -
Coordinates 2219317..2219417 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BFI33_RS11500 2214388..2214615 - 228 WP_004399298.1 helix-turn-helix transcriptional regulator -
BFI33_RS11505 2214876..2216192 - 1317 WP_004399369.1 hypothetical protein -
BFI33_RS11510 2216549..2217055 - 507 WP_004399486.1 hypothetical protein -
BFI33_RS11515 2217383..2218615 - 1233 WP_004399445.1 hypothetical protein -
BFI33_RS11520 2218697..2218885 - 189 WP_004399547.1 hypothetical protein -
BFI33_RS22390 2218930..2219181 - 252 WP_010886546.1 hypothetical protein -
BFI33_RS11525 2219200..2219376 - 177 WP_009967515.1 hypothetical protein Toxin
- 2219317..2219417 + 101 NuclAT_2 - Antitoxin
- 2219317..2219417 + 101 NuclAT_2 - Antitoxin
- 2219317..2219417 + 101 NuclAT_2 - Antitoxin
- 2219317..2219417 + 101 NuclAT_2 - Antitoxin
BFI33_RS11530 2219751..2220362 - 612 WP_009967516.1 lipoprotein -
BFI33_RS11535 2220477..2220803 - 327 WP_009967517.1 helix-turn-helix domain-containing protein -
BFI33_RS11540 2221756..2221950 + 195 WP_004399291.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2151042..2285804 134762


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6882.45 Da        Isoelectric Point: 12.8833

>T65210 WP_009967515.1 NZ_CP016852:c2219376-2219200 [Bacillus subtilis subsp. subtilis]
VLEKMGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Download         Length: 177 bp

>T65210 NZ_CP016852:c2219376-2219200 [Bacillus subtilis subsp. subtilis]
GTGCTTGAGAAAATGGGTATCGTAGTTGCTTTCCTCATATCTTTAACGGTTCTTACAATCAACAGTCTAACAATAGTTGA
GAAGGTAAGAAACCTAAAGAATGGGACAAGCAAAAAGAAAAAGCGTATACGCAAGCGGCTCCGACCAAAGAGACAACGCC
AACGTATACGCCGATGA

Antitoxin


Download         Length: 101 bp

>AT65210 NZ_CP016852:2219317-2219417 [Bacillus subtilis subsp. subtilis]
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTACGATACCCATTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB O31941

Antitoxin

Download structure file

References