Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) yonT-SR6/-
Location 2214745..2215074 Replicon chromosome
Accession NZ_AP019714
Organism Bacillus subtilis subsp. subtilis strain NBRC 13719

Toxin (Protein)


Gene name yonT Uniprot ID C0H439
Locus tag FNP71_RS11535 Protein ID WP_010886546.1
Coordinates 2214745..2214996 (-) Length 84 a.a.

Antitoxin (RNA)


Gene name SR6
Locus tag -
Coordinates 2214974..2215074 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FNP71_RS11510 2210203..2210430 - 228 WP_004399298.1 helix-turn-helix transcriptional regulator -
FNP71_RS11515 2210691..2212007 - 1317 WP_004399369.1 hypothetical protein -
FNP71_RS11520 2212364..2212870 - 507 WP_004399486.1 hypothetical protein -
FNP71_RS11525 2213198..2214430 - 1233 WP_004399445.1 hypothetical protein -
FNP71_RS11530 2214512..2214700 - 189 WP_004399547.1 hypothetical protein -
FNP71_RS11535 2214745..2214996 - 252 WP_010886546.1 hypothetical protein Toxin
- 2214974..2215074 + 101 - - Antitoxin
FNP71_RS11540 2215015..2215191 - 177 WP_009967515.1 hypothetical protein -
- 2215132..2215232 + 101 NuclAT_2 - -
- 2215132..2215232 + 101 NuclAT_2 - -
- 2215132..2215232 + 101 NuclAT_2 - -
- 2215132..2215232 + 101 NuclAT_2 - -
FNP71_RS11545 2215566..2216177 - 612 WP_009967516.1 lipoprotein -
FNP71_RS11550 2216292..2216618 - 327 WP_009967517.1 helix-turn-helix domain-containing protein -
FNP71_RS11555 2217571..2217765 + 195 WP_004399291.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2146857..2295886 149029


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9956.96 Da        Isoelectric Point: 9.7930

>T32934 WP_010886546.1 NZ_AP019714:c2214996-2214745 [Bacillus subtilis subsp. subtilis]
MNFSFSSYPYYNMIKHIANMKRFSLWFTHITFIGLFLMFQLIKDYFSSEGQALINTIFVVTCIIAILLWIIYCVFLKLRN
KSH

Download         Length: 252 bp

>T32934 NZ_AP019714:c2214996-2214745 [Bacillus subtilis subsp. subtilis]
ATGAACTTCTCCTTTAGTTCCTACCCATATTATAACATGATCAAGCACATTGCAAACATGAAACGATTCTCATTATGGTT
TACCCATATCACATTCATTGGCTTATTCTTAATGTTTCAACTCATCAAAGATTACTTCAGCAGCGAAGGACAGGCGCTAA
TCAACACAATTTTTGTTGTCACATGTATCATTGCCATATTGTTATGGATCATCTATTGTGTATTCCTTAAACTAAGAAAC
AAGTCACACTAA

Antitoxin


Download         Length: 101 bp

>AT32934 NZ_AP019714:2214974-2215074 [Bacillus subtilis subsp. subtilis]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCGGCGTATACGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB C0H439

Antitoxin

Download structure file

References