Detailed information of TA system TA153027

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): yonT-SR6/-
• Location: 2213044..2213261
• Replicon: chromosome
• Accession: NZ_CP050532
• Organism: Bacillus subtilis subsp. subtilis str. SMY

Toxin (Protein)

• Gene name: yonT
• Uniprot ID: O31941
• Locus tag: HCN55_RS11360
• Protein ID: WP_009967515.1
• Coordinates: 2213085..2213261 (-)
• Length: 59 a.a.

Antitoxin (RNA)

Gene name	SR6
Locus tag	-
Coordinates	2213044..2213144 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HCN55_RS11330	2208273..2208500	-	228	WP_004399298.1	helix-turn-helix transcriptional regulator	-
HCN55_RS11335	2208761..2210077	-	1317	WP_004399369.1	hypothetical protein	-
HCN55_RS11340	2210434..2210940	-	507	WP_004399486.1	hypothetical protein	-
HCN55_RS11345	2211268..2212500	-	1233	WP_004399445.1	hypothetical protein	-
HCN55_RS11350	2212582..2212770	-	189	WP_004399547.1	hypothetical protein	-
HCN55_RS11355	2212815..2213066	-	252	WP_010886546.1	hypothetical protein	-
-	2213044..2213144	+	101	-	-	Antitoxin
HCN55_RS11360	2213085..2213261	-	177	WP_009967515.1	hypothetical protein	Toxin
-	2213202..2213302	+	101	NuclAT_2	-	-
-	2213202..2213302	+	101	NuclAT_2	-	-
-	2213202..2213302	+	101	NuclAT_2	-	-
-	2213202..2213302	+	101	NuclAT_2	-	-
HCN55_RS11365	2213636..2214247	-	612	WP_009967516.1	lipoprotein	-
HCN55_RS11370	2214362..2214688	-	327	WP_009967517.1	helix-turn-helix domain-containing protein	-
HCN55_RS11375	2215641..2215835	+	195	WP_004399291.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	Similar MGE(s) Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE. Detail Genome accession Organism MGE type Related TA Coordinates Mash distance View NC_000964 Bacillus subtilis subsp. subtilis str. 168 Prophage TA006323, TA006321, TA06323b, TA020252 2151626..2286408 0	inside	Prophage	-	-	2144927..2279709	134782

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 59 a.a.
• Molecular weight: 6882.45 Da
• Isoelectric Point: 12.8833

>T153027 WP_009967515.1 NZ_CP050532:c2213261-2213085 [Bacillus subtilis subsp. subtilis str. SMY]
VLEKMGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Nucleotide

• Length: 177 bp

>T153027 NZ_CP066748:358205-358732 [Escherichia coli O157:H7]
ATGGATGATCTGACGATAGAGATTCTGACCGATGATGCAGATTATGATCTACAGCGATTCGACTGCGGCGAGGAAGCGTT
AAATCTCTTTCTGACGACACATCTCGTTCGTCAACATCGCAACAAAATTCTGCGAGCGTATATCCTTTGTCGCAACACTC
CAGAACGTCAGGTGCTGGGATATTACACATTATGCGGCAGTTGTTTTGAACGAGCCGCATTGCCCTCGAAATCGAAACAG
AAAAAAATTCCCTACAAAAATATTCCCAGCGTTACTCTTGGGCGTCTGGCAATTGATCGTTCATTACAGGGGCAGGGATG
GGGAGCAACACTGGTTGCTCATGCCATGAAAGTCGTCTGGTCAGCCTCTTTAGCGGTAGGTATTCACGGTCTTTTTGTCG
AGGCGCTGAATGAAAAAGCCCATACGTTTTATAAATCGCTGGGCTTTATCCCTTTAGTCGGGGAAAACGAAAATGCGTTA
TTTTTCCCAACCAAATCCATTGAACTGCTTTTTACACAGAGCGATTAA

Antitoxin

Nucleotide

• Length: 101 bp

>AT153027 NZ_CP050532:2213044-2213144 [Bacillus subtilis subsp. subtilis str. SMY]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCGGCGTATACGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Structures

Toxin

• AlphaFold DB: O31941

Antitoxin