Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) yonT-SR6/-
Location 2237753..2237970 Replicon chromosome
Accession NZ_LN649259
Organism Bacillus subtilis strain BS49

Toxin (Protein)


Gene name yonT Uniprot ID O31941
Locus tag VV34_RS22940 Protein ID WP_009967515.1
Coordinates 2237794..2237970 (-) Length 59 a.a.

Antitoxin (RNA)


Gene name SR6
Locus tag -
Coordinates 2237753..2237853 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
VV34_RS11585 2232982..2233209 - 228 WP_004399298.1 helix-turn-helix transcriptional regulator -
VV34_RS11590 2233470..2234786 - 1317 WP_004399369.1 hypothetical protein -
VV34_RS11595 2235143..2235649 - 507 WP_004399486.1 hypothetical protein -
VV34_RS11600 2235977..2237209 - 1233 WP_004399445.1 hypothetical protein -
VV34_RS11605 2237291..2237479 - 189 WP_004399547.1 hypothetical protein -
VV34_RS22935 2237524..2237775 - 252 WP_010886546.1 hypothetical protein -
- 2237753..2237853 + 101 - - Antitoxin
VV34_RS22940 2237794..2237970 - 177 WP_009967515.1 hypothetical protein Toxin
- 2237911..2238011 + 101 NuclAT_2 - -
- 2237911..2238011 + 101 NuclAT_2 - -
- 2237911..2238011 + 101 NuclAT_2 - -
- 2237911..2238011 + 101 NuclAT_2 - -
VV34_RS11615 2238345..2238956 - 612 WP_009967516.1 lipoprotein -
VV34_RS11620 2239071..2239397 - 327 WP_009967517.1 helix-turn-helix domain-containing protein -
VV34_RS11625 2240350..2240544 + 195 WP_004399291.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2169638..2304418 134780


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6882.45 Da        Isoelectric Point: 12.8833

>T285507 WP_009967515.1 NZ_LN649259:c2237970-2237794 [Bacillus subtilis]
VLEKMGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Download         Length: 177 bp

Antitoxin


Download         Length: 101 bp

>AT285507 NZ_LN649259:2237753-2237853 [Bacillus subtilis]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCGGCGTATACGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB O31941

Antitoxin

Download structure file

References