Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) yonT-as-bsrG/-
Location 3049836..3050053 Replicon chromosome
Accession NZ_CP064093
Organism Bacillus subtilis strain N1282-4at

Toxin (Protein)


Gene name yonT Uniprot ID O31941
Locus tag IRJ24_RS16145 Protein ID WP_009967515.1
Coordinates 3049877..3050053 (+) Length 59 a.a.

Antitoxin (RNA)


Gene name as-bsrG
Locus tag -
Coordinates 3049836..3049936 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IRJ24_RS16130 (3047303) 3047303..3047497 - 195 WP_004399291.1 hypothetical protein -
IRJ24_RS16135 (3048450) 3048450..3048776 + 327 WP_009967517.1 helix-turn-helix transcriptional regulator -
IRJ24_RS16140 (3048891) 3048891..3049502 + 612 WP_009967516.1 lipoprotein -
- (3049836) 3049836..3049936 - 101 NuclAT_2 - Antitoxin
- (3049836) 3049836..3049936 - 101 NuclAT_2 - Antitoxin
- (3049836) 3049836..3049936 - 101 NuclAT_2 - Antitoxin
- (3049836) 3049836..3049936 - 101 NuclAT_2 - Antitoxin
IRJ24_RS16145 (3049877) 3049877..3050053 + 177 WP_009967515.1 hypothetical protein Toxin
IRJ24_RS16150 (3050072) 3050072..3050323 + 252 WP_010886546.1 hypothetical protein -
IRJ24_RS16155 (3050368) 3050368..3050556 + 189 WP_004399547.1 hypothetical protein -
IRJ24_RS16160 (3050638) 3050638..3051870 + 1233 WP_004399445.1 hypothetical protein -
IRJ24_RS16165 (3052198) 3052198..3052704 + 507 WP_004399486.1 hypothetical protein -
IRJ24_RS16170 (3053061) 3053061..3054377 + 1317 WP_004399369.1 hypothetical protein -
IRJ24_RS16175 (3054638) 3054638..3054865 + 228 WP_004399298.1 helix-turn-helix transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2982784..3118211 135427


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6882.45 Da        Isoelectric Point: 12.8833

>T180039 WP_009967515.1 NZ_CP064093:3049877-3050053 [Bacillus subtilis]
VLEKMGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Download         Length: 177 bp

>T180039 NZ_CP085056:1816066-1816317 [Escherichia coli]
ATGCGTACAATTAGTTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATTATTGAGTGA

Antitoxin


Download         Length: 101 bp

>AT180039 NZ_CP064093:c3049936-3049836 [Bacillus subtilis]
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTACGATACCCATTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB O31941

Antitoxin

Download structure file

References