Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) yonT-SR6/-
Location 2191958..2192175 Replicon chromosome
Accession NZ_AP024627
Organism Bacillus subtilis strain BEST3136

Toxin (Protein)


Gene name yonT Uniprot ID O31941
Locus tag K6J86_RS11220 Protein ID WP_009967515.1
Coordinates 2191999..2192175 (-) Length 59 a.a.

Antitoxin (RNA)


Gene name SR6
Locus tag -
Coordinates 2191958..2192058 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6J86_RS11190 2187187..2187414 - 228 WP_004399298.1 helix-turn-helix transcriptional regulator -
K6J86_RS11195 2187675..2188991 - 1317 WP_004399369.1 hypothetical protein -
K6J86_RS11200 2189348..2189854 - 507 WP_004399486.1 hypothetical protein -
K6J86_RS11205 2190182..2191414 - 1233 WP_004399445.1 hypothetical protein -
K6J86_RS11210 2191496..2191684 - 189 WP_004399547.1 hypothetical protein -
K6J86_RS11215 2191729..2191980 - 252 WP_010886546.1 hypothetical protein -
- 2191958..2192058 + 101 - - Antitoxin
K6J86_RS11220 2191999..2192175 - 177 WP_009967515.1 hypothetical protein Toxin
- 2192116..2192216 + 101 NuclAT_2 - -
- 2192116..2192216 + 101 NuclAT_2 - -
- 2192116..2192216 + 101 NuclAT_2 - -
- 2192116..2192216 + 101 NuclAT_2 - -
K6J86_RS11225 2192550..2193161 - 612 WP_009967516.1 lipoprotein -
K6J86_RS11230 2193276..2193602 - 327 WP_009967517.1 helix-turn-helix transcriptional regulator -
K6J86_RS11235 2194555..2194749 + 195 WP_004399291.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2123843..2258623 134780


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6882.45 Da        Isoelectric Point: 12.8833

>T39107 WP_009967515.1 NZ_AP024627:c2192175-2191999 [Bacillus subtilis]
VLEKMGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Download         Length: 177 bp

>T39107 NZ_AP024627:c2192175-2191999 [Bacillus subtilis]
GTGCTTGAGAAAATGGGTATCGTAGTTGCTTTCCTCATATCTTTAACGGTTCTTACAATCAACAGTCTAACAATAGTTGA
GAAGGTAAGAAACCTAAAGAATGGGACAAGCAAAAAGAAAAAGCGTATACGCAAGCGGCTCCGACCAAAGAGACAACGCC
AACGTATACGCCGATGA

Antitoxin


Download         Length: 101 bp

>AT39107 NZ_AP024627:2191958-2192058 [Bacillus subtilis]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCGGCGTATACGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB O31941

Antitoxin

Download structure file

References