Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | bsrG-as-bsrH/- |
Location | 2239428..2239718 | Replicon | chromosome |
Accession | NZ_AP024626 | ||
Organism | Bacillus subtilis strain BEST3125 |
Toxin (Protein)
Gene name | bsrG | Uniprot ID | L8EAY0 |
Locus tag | K6K02_RS11490 | Protein ID | WP_009967548.1 |
Coordinates | 2239428..2239544 (+) | Length | 39 a.a. |
Antitoxin (RNA)
Gene name | as-bsrH | ||
Locus tag | - | ||
Coordinates | 2239539..2239718 (-) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
K6K02_RS11455 (2235355) | 2235355..2235525 | - | 171 | WP_009967544.1 | bacteriocin sublancin-168 | - |
K6K02_RS11460 (2235822) | 2235822..2236139 | - | 318 | WP_009967545.1 | sublancin immunity protein SunI | - |
K6K02_RS11465 (2236241) | 2236241..2237491 | - | 1251 | WP_004398504.1 | UV-damage repair protein uvrX | - |
K6K02_RS11470 (2237484) | 2237484..2237816 | - | 333 | WP_004398710.1 | YolD-like family protein | - |
K6K02_RS11475 (2237990) | 2237990..2238325 | + | 336 | WP_004399073.1 | hypothetical protein | - |
K6K02_RS11480 (2238368) | 2238368..2238724 | - | 357 | WP_004398595.1 | hypothetical protein | - |
K6K02_RS11485 (2238730) | 2238730..2239197 | - | 468 | WP_003246138.1 | YolA family protein | - |
K6K02_RS11490 (2239428) | 2239428..2239544 | + | 117 | WP_009967548.1 | type I toxin-antitoxin system toxin BsrG | Toxin |
- (2239539) | 2239539..2239718 | - | 180 | NuclAT_1 | - | Antitoxin |
- (2239539) | 2239539..2239718 | - | 180 | NuclAT_1 | - | Antitoxin |
- (2239539) | 2239539..2239718 | - | 180 | NuclAT_1 | - | Antitoxin |
- (2239539) | 2239539..2239718 | - | 180 | NuclAT_1 | - | Antitoxin |
K6K02_RS11495 (2239823) | 2239823..2240356 | - | 534 | WP_004399156.1 | GNAT family protein | - |
K6K02_RS11500 (2240392) | 2240392..2240970 | - | 579 | WP_004399123.1 | SMI1/KNR4 family protein | - |
K6K02_RS11505 (2241034) | 2241034..2241531 | - | 498 | WP_003246188.1 | SMI1/KNR4 family protein | - |
K6K02_RS11510 (2241540) | 2241540..2243255 | - | 1716 | WP_004398855.1 | ribonuclease YeeF family protein | - |
K6K02_RS11515 (2243355) | 2243355..2243912 | - | 558 | WP_003246042.1 | SMI1/KNR4 family protein | - |
K6K02_RS11520 (2244047) | 2244047..2244181 | + | 135 | WP_234047931.1 | transposase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
inside | Prophage | - | - | 2117462..2266489 | 149027 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 39 a.a. Molecular weight: 4336.39 Da Isoelectric Point: 10.1022
>T39091 WP_009967548.1 NZ_AP024626:2239428-2239544 [Bacillus subtilis]
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK
Download Length: 117 bp
>T39091 NZ_AP024626:2239428-2239544 [Bacillus subtilis]
ATGACTGTTTACGAATCATTAATGATAATGATCAATTTTGGCGGATTGATATTAAATACCGTCTTGTTGATCTTCAATAT
AATGATGATTGTAACGTCAAGCCAAAAGAAAAAATAG
ATGACTGTTTACGAATCATTAATGATAATGATCAATTTTGGCGGATTGATATTAAATACCGTCTTGTTGATCTTCAATAT
AATGATGATTGTAACGTCAAGCCAAAAGAAAAAATAG
Antitoxin
Download Length: 180 bp
>AT39091 NZ_AP024626:c2239718-2239539 [Bacillus subtilis]
AATGATACAATTATATAATTATTTTTTGCATTTTGTTTAATTAAATGCATAAAATAAAAAGACCAGGGTGTTGGTAGCAC
CCTGGCTCTGTACAAAAGCTGCCCATCAAAGGGCTTGCTCGTTGTCAAATCTGCGTAGGCCTAACCCTTCAGGTGTCCAA
ACTCAAGGGAAGGTCTATTT
AATGATACAATTATATAATTATTTTTTGCATTTTGTTTAATTAAATGCATAAAATAAAAAGACCAGGGTGTTGGTAGCAC
CCTGGCTCTGTACAAAAGCTGCCCATCAAAGGGCTTGCTCGTTGTCAAATCTGCGTAGGCCTAACCCTTCAGGTGTCCAA
ACTCAAGGGAAGGTCTATTT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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