Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) bsrG-as-bsrH/-
Location 2273626..2273916 Replicon chromosome
Accession NZ_CP020102
Organism Bacillus subtilis strain NCIB 3610

Toxin (Protein)


Gene name bsrG Uniprot ID L8EAY0
Locus tag B4U62_RS22820 Protein ID WP_009967548.1
Coordinates 2273626..2273742 (+) Length 39 a.a.

Antitoxin (RNA)


Gene name as-bsrH
Locus tag -
Coordinates 2273737..2273916 (-)

Genomic Context

B4U62_RS11705B4U62_RS22820B4U62_RS11745B4U62_RS11685B4U62_RS11690B4U62_RS11695B4U62_RS11700B4U62_RS11710B4U62_RS11715-----B4U62_RS11720B4U62_RS11725B4U62_RS11730B4U62_RS11735B4U62_RS11740
Location: 2272188..2272523 (336 bp)
Type: Others
Protein ID: WP_004399073.1
Location: 2273626..2273742 (117 bp)
Type: Toxin
Protein ID: WP_009967548.1
Location: 2278194..2278379 (186 bp)
Type: Others
Protein ID: WP_003245951.1
Location: 2269553..2269723 (171 bp)
Type: Others
Protein ID: WP_009967544.1
Location: 2270020..2270337 (318 bp)
Type: Others
Protein ID: WP_009967545.1
Location: 2270439..2271689 (1251 bp)
Type: Others
Protein ID: WP_004398504.1
Location: 2271682..2272014 (333 bp)
Type: Others
Protein ID: WP_004398710.1
Location: 2272566..2272922 (357 bp)
Type: Others
Protein ID: WP_004398595.1
Location: 2272928..2273395 (468 bp)
Type: Others
Protein ID: WP_003246138.1
Location: 2273737..2273916 (180 bp)
Type: Antitoxin
Protein ID: NuclAT_1
Location: 2273737..2273916 (180 bp)
Type: Antitoxin
Protein ID: NuclAT_1
Location: 2273737..2273916 (180 bp)
Type: Antitoxin
Protein ID: NuclAT_1
Location: 2273737..2273916 (180 bp)
Type: Antitoxin
Protein ID: NuclAT_1
Location: 2274021..2274554 (534 bp)
Type: Others
Protein ID: WP_004399156.1
Location: 2274590..2275168 (579 bp)
Type: Others
Protein ID: WP_004399123.1
Location: 2275232..2275729 (498 bp)
Type: Others
Protein ID: WP_003246188.1
Location: 2275738..2277453 (1716 bp)
Type: Others
Protein ID: WP_004398855.1
Location: 2277553..2278110 (558 bp)
Type: Others
Protein ID: WP_003246042.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
B4U62_RS116852269553..2269723-171WP_009967544.1bacteriocin sublancin-168-
B4U62_RS116902270020..2270337-318WP_009967545.1sublancin immunity protein SunI-
B4U62_RS116952270439..2271689-1251WP_004398504.1UV-damage repair protein uvrX-
B4U62_RS117002271682..2272014-333WP_004398710.1YolD-like family protein-
B4U62_RS117052272188..2272523+336WP_004399073.1hypothetical protein-
B4U62_RS117102272566..2272922-357WP_004398595.1hypothetical protein-
B4U62_RS117152272928..2273395-468WP_003246138.1YolA family protein-
B4U62_RS228202273626..2273742+117WP_009967548.1type I toxin-antitoxin system toxin BsrGToxin
-2273737..2273916-180NuclAT_1-Antitoxin
-2273737..2273916-180NuclAT_1-Antitoxin
-2273737..2273916-180NuclAT_1-Antitoxin
-2273737..2273916-180NuclAT_1-Antitoxin
B4U62_RS117202274021..2274554-534WP_004399156.1GNAT family N-acetyltransferase-
B4U62_RS117252274590..2275168-579WP_004399123.1SMI1/KNR4 family protein-
B4U62_RS117302275232..2275729-498WP_003246188.1SMI1/KNR4 family protein-
B4U62_RS117352275738..2277453-1716WP_004398855.1ribonuclease YeeF family protein-
B4U62_RS117402277553..2278110-558WP_003246042.1SMI1/KNR4 family protein-
B4U62_RS117452278194..2278379+186WP_003245951.1transposase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
insideProphage--2151659..2286440134781


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(1-38)


Sequences

Toxin        


Download         Length: 39 a.a.        Molecular weight: 4336.39 Da        Isoelectric Point: 10.1022

>T74090 WP_009967548.1 NZ_CP020102:2273626-2273742 [Bacillus subtilis]
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK

Download         Length: 117 bp

>T74090 NZ_CP020102:2273626-2273742 [Bacillus subtilis]
ATGACTGTTTACGAATCATTAATGATAATGATCAATTTTGGCGGATTGATATTAAATACCGTCTTGTTGATCTTCAATAT
AATGATGATTGTAACGTCAAGCCAAAAGAAAAAATAG

Antitoxin


Download         Length: 180 bp

>AT74090 NZ_CP020102:c2273916-2273737 [Bacillus subtilis]
AATGATACAATTATATAATTATTTTTTGCATTTTGTTTAATTAAATGCATAAAATAAAAAGACCAGGGTGTTGGTAGCAC
CCTGGCTCTGTACAAAAGCTGCCCATCAAAGGGCTTGCTCGTTGTCAAATCTGCGTAGGCCTAACCCTTCAGGTGTCCAA
ACTCAAGGGAAGGTCTATTT

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A7Z7EVU9

Antitoxin

Download structure file

References