Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) bsrG-as-bsrH/-
Location 2273626..2273916 Replicon chromosome
Accession NZ_CP020102
Organism Bacillus subtilis strain NCIB 3610

Toxin (Protein)


Gene name bsrG Uniprot ID L8EAY0
Locus tag B4U62_RS22820 Protein ID WP_009967548.1
Coordinates 2273626..2273742 (+) Length 39 a.a.

Antitoxin (RNA)


Gene name as-bsrH
Locus tag -
Coordinates 2273737..2273916 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B4U62_RS11685 2269553..2269723 - 171 WP_009967544.1 bacteriocin sublancin-168 -
B4U62_RS11690 2270020..2270337 - 318 WP_009967545.1 sublancin immunity protein SunI -
B4U62_RS11695 2270439..2271689 - 1251 WP_004398504.1 UV-damage repair protein uvrX -
B4U62_RS11700 2271682..2272014 - 333 WP_004398710.1 YolD-like family protein -
B4U62_RS11705 2272188..2272523 + 336 WP_004399073.1 hypothetical protein -
B4U62_RS11710 2272566..2272922 - 357 WP_004398595.1 hypothetical protein -
B4U62_RS11715 2272928..2273395 - 468 WP_003246138.1 YolA family protein -
B4U62_RS22820 2273626..2273742 + 117 WP_009967548.1 type I toxin-antitoxin system toxin BsrG Toxin
- 2273737..2273916 - 180 NuclAT_1 - Antitoxin
- 2273737..2273916 - 180 NuclAT_1 - Antitoxin
- 2273737..2273916 - 180 NuclAT_1 - Antitoxin
- 2273737..2273916 - 180 NuclAT_1 - Antitoxin
B4U62_RS11720 2274021..2274554 - 534 WP_004399156.1 GNAT family N-acetyltransferase -
B4U62_RS11725 2274590..2275168 - 579 WP_004399123.1 SMI1/KNR4 family protein -
B4U62_RS11730 2275232..2275729 - 498 WP_003246188.1 SMI1/KNR4 family protein -
B4U62_RS11735 2275738..2277453 - 1716 WP_004398855.1 ribonuclease YeeF family protein -
B4U62_RS11740 2277553..2278110 - 558 WP_003246042.1 SMI1/KNR4 family protein -
B4U62_RS11745 2278194..2278379 + 186 WP_003245951.1 transposase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2151659..2286440 134781


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(1-38)


Sequences


Toxin        


Download         Length: 39 a.a.        Molecular weight: 4336.39 Da        Isoelectric Point: 10.1022

>T74090 WP_009967548.1 NZ_CP020102:2273626-2273742 [Bacillus subtilis]
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK

Download         Length: 117 bp

>T74090 NZ_CP020102:2273626-2273742 [Bacillus subtilis]
ATGACTGTTTACGAATCATTAATGATAATGATCAATTTTGGCGGATTGATATTAAATACCGTCTTGTTGATCTTCAATAT
AATGATGATTGTAACGTCAAGCCAAAAGAAAAAATAG

Antitoxin


Download         Length: 180 bp

>AT74090 NZ_CP020102:c2273916-2273737 [Bacillus subtilis]
AATGATACAATTATATAATTATTTTTTGCATTTTGTTTAATTAAATGCATAAAATAAAAAGACCAGGGTGTTGGTAGCAC
CCTGGCTCTGTACAAAAGCTGCCCATCAAAGGGCTTGCTCGTTGTCAAATCTGCGTAGGCCTAACCCTTCAGGTGTCCAA
ACTCAAGGGAAGGTCTATTT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A7Z7EVU9


Antitoxin

Download structure file

References