Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) bsrG-as-bsrH/-
Location 2268818..2269108 Replicon chromosome
Accession NZ_CP094361
Organism Bacillus subtilis strain NCIB 3610

Toxin (Protein)


Gene name bsrG Uniprot ID L8EAY0
Locus tag MQC90_RS11745 Protein ID WP_009967548.1
Coordinates 2268818..2268934 (+) Length 39 a.a.

Antitoxin (RNA)


Gene name as-bsrH
Locus tag -
Coordinates 2268929..2269108 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MQC90_RS11710 (2264745) 2264745..2264915 - 171 WP_009967544.1 bacteriocin sublancin-168 -
MQC90_RS11715 (2265212) 2265212..2265529 - 318 WP_009967545.1 sublancin immunity protein SunI -
MQC90_RS11720 (2265631) 2265631..2266881 - 1251 WP_004398504.1 UV-damage repair protein uvrX -
MQC90_RS11725 (2266874) 2266874..2267206 - 333 WP_004398710.1 YolD-like family protein -
MQC90_RS11730 (2267380) 2267380..2267715 + 336 WP_004399073.1 hypothetical protein -
MQC90_RS11735 (2267758) 2267758..2268114 - 357 WP_004398595.1 hypothetical protein -
MQC90_RS11740 (2268120) 2268120..2268587 - 468 WP_003246138.1 YolA family protein -
MQC90_RS11745 (2268818) 2268818..2268934 + 117 WP_009967548.1 type I toxin-antitoxin system toxin BsrG Toxin
- (2268929) 2268929..2269108 - 180 NuclAT_1 - Antitoxin
- (2268929) 2268929..2269108 - 180 NuclAT_1 - Antitoxin
- (2268929) 2268929..2269108 - 180 NuclAT_1 - Antitoxin
- (2268929) 2268929..2269108 - 180 NuclAT_1 - Antitoxin
MQC90_RS11750 (2269213) 2269213..2269746 - 534 WP_004399156.1 GNAT family protein -
MQC90_RS11755 (2269782) 2269782..2270360 - 579 WP_004399123.1 SMI1/KNR4 family protein -
MQC90_RS11760 (2270424) 2270424..2270921 - 498 WP_003246188.1 SMI1/KNR4 family protein -
MQC90_RS11765 (2270930) 2270930..2272645 - 1716 WP_004398855.1 ribonuclease YeeF family protein -
MQC90_RS11770 (2272745) 2272745..2273302 - 558 WP_003246042.1 SMI1/KNR4 family protein -
MQC90_RS11775 (2273437) 2273437..2273571 + 135 WP_234047931.1 transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2146850..2307109 160259


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(1-38)


Sequences

Toxin        


Download         Length: 39 a.a.        Molecular weight: 4336.39 Da        Isoelectric Point: 10.1022

>T239797 WP_009967548.1 NZ_CP094361:2268818-2268934 [Bacillus subtilis]
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK

Download         Length: 117 bp

>T239797 NZ_LS483324:c1946983-1946831 [Staphylococcus aureus]
ATGTCTAAAGACAAAGATCCAAAATTAAATTATCATGAAGAAGAAAACAGTATGGTAACTGATTTTGAAGATTTAAAAGA
ATTAGGTAAAGAAATGGAACAAATTTCTGATCAAAATGATCAAGAAAAGAATTCTGAAGAAGACAGTCAGTAA

Antitoxin


Download         Length: 180 bp

>AT239797 NZ_CP094361:c2269108-2268929 [Bacillus subtilis]
AATGATACAATTATATAATTATTTTTTGCATTTTGTTTAATTAAATGCATAAAATAAAAAGACCAGGGTGTTGGTAGCAC
CCTGGCTCTGTACAAAAGCTGCCCATCAAAGGGCTTGCTCGTTGTCAAATCTGCGTAGGCCTAACCCTTCAGGTGTCCAA
ACTCAAGGGAAGGTCTATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7Z7EVU9

Antitoxin

Download structure file

References