Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) yonT-as-bsrG/-
Location 2219413..2219630 Replicon chromosome
Accession NZ_CP032310
Organism Bacillus subtilis strain WB800N

Toxin (Protein)


Gene name yonT Uniprot ID O31941
Locus tag D3Z87_RS11540 Protein ID WP_009967515.1
Coordinates 2219413..2219589 (-) Length 59 a.a.

Antitoxin (RNA)


Gene name as-bsrG
Locus tag -
Coordinates 2219530..2219630 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D3Z87_RS11510 2214601..2214828 - 228 WP_004399298.1 helix-turn-helix transcriptional regulator -
D3Z87_RS11515 2215089..2216405 - 1317 WP_004399369.1 hypothetical protein -
D3Z87_RS11520 2216762..2217268 - 507 WP_004399486.1 hypothetical protein -
D3Z87_RS11525 2217596..2218828 - 1233 WP_004399445.1 hypothetical protein -
D3Z87_RS11530 2218910..2219098 - 189 WP_004399547.1 hypothetical protein -
D3Z87_RS11535 2219143..2219394 - 252 WP_010886546.1 hypothetical protein -
D3Z87_RS11540 2219413..2219589 - 177 WP_009967515.1 hypothetical protein Toxin
- 2219530..2219630 + 101 NuclAT_2 - Antitoxin
- 2219530..2219630 + 101 NuclAT_2 - Antitoxin
- 2219530..2219630 + 101 NuclAT_2 - Antitoxin
- 2219530..2219630 + 101 NuclAT_2 - Antitoxin
D3Z87_RS11545 2219964..2220575 - 612 WP_009967516.1 lipoprotein -
D3Z87_RS11550 2220690..2221016 - 327 WP_009967517.1 helix-turn-helix domain-containing protein -
D3Z87_RS11555 2221969..2222163 + 195 WP_004399291.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2151258..2286037 134779


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-137)


Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6882.45 Da        Isoelectric Point: 12.8833

>T111625 WP_009967515.1 NZ_CP032310:c2219589-2219413 [Bacillus subtilis]
VLEKMGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Download         Length: 177 bp

>T111625 NZ_CP032310:c2219589-2219413 [Bacillus subtilis]
GTGCTTGAGAAAATGGGTATCGTAGTTGCTTTCCTCATATCTTTAACGGTTCTTACAATCAACAGTCTAACAATAGTTGA
GAAGGTAAGAAACCTAAAGAATGGGACAAGCAAAAAGAAAAAGCGTATACGCAAGCGGCTCCGACCAAAGAGACAACGCC
AACGTATACGCCGATGA

Antitoxin


Download         Length: 101 bp

>AT111625 NZ_CP032310:2219530-2219630 [Bacillus subtilis]
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTACGATACCCATTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB O31941

Antitoxin

Download structure file

References