Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) yonT-as-bsrG/-
Location 2219413..2219630 Replicon chromosome
Accession NZ_CP032310
Organism Bacillus subtilis strain WB800N

Toxin (Protein)


Gene name yonT Uniprot ID O31941
Locus tag D3Z87_RS11540 Protein ID WP_009967515.1
Coordinates 2219413..2219589 (-) Length 59 a.a.

Antitoxin (RNA)


Gene name as-bsrG
Locus tag -
Coordinates 2219530..2219630 (+)

Genomic Context

-----D3Z87_RS11555D3Z87_RS11510D3Z87_RS11515D3Z87_RS11520D3Z87_RS11525D3Z87_RS11530D3Z87_RS11535D3Z87_RS11540D3Z87_RS11545D3Z87_RS11550
Location: 2219530..2219630 (101 bp)
Type: Antitoxin
Protein ID: NuclAT_2
Location: 2219530..2219630 (101 bp)
Type: Antitoxin
Protein ID: NuclAT_2
Location: 2219530..2219630 (101 bp)
Type: Antitoxin
Protein ID: NuclAT_2
Location: 2219530..2219630 (101 bp)
Type: Antitoxin
Protein ID: NuclAT_2
Location: 2221969..2222163 (195 bp)
Type: Others
Protein ID: WP_004399291.1
Location: 2214601..2214828 (228 bp)
Type: Others
Protein ID: WP_004399298.1
Location: 2215089..2216405 (1317 bp)
Type: Others
Protein ID: WP_004399369.1
Location: 2216762..2217268 (507 bp)
Type: Others
Protein ID: WP_004399486.1
Location: 2217596..2218828 (1233 bp)
Type: Others
Protein ID: WP_004399445.1
Location: 2218910..2219098 (189 bp)
Type: Others
Protein ID: WP_004399547.1
Location: 2219143..2219394 (252 bp)
Type: Others
Protein ID: WP_010886546.1
Location: 2219413..2219589 (177 bp)
Type: Toxin
Protein ID: WP_009967515.1
Location: 2219964..2220575 (612 bp)
Type: Others
Protein ID: WP_009967516.1
Location: 2220690..2221016 (327 bp)
Type: Others
Protein ID: WP_009967517.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
D3Z87_RS115102214601..2214828-228WP_004399298.1helix-turn-helix transcriptional regulator-
D3Z87_RS115152215089..2216405-1317WP_004399369.1hypothetical protein-
D3Z87_RS115202216762..2217268-507WP_004399486.1hypothetical protein-
D3Z87_RS115252217596..2218828-1233WP_004399445.1hypothetical protein-
D3Z87_RS115302218910..2219098-189WP_004399547.1hypothetical protein-
D3Z87_RS115352219143..2219394-252WP_010886546.1hypothetical protein-
D3Z87_RS115402219413..2219589-177WP_009967515.1hypothetical proteinToxin
-2219530..2219630+101NuclAT_2-Antitoxin
-2219530..2219630+101NuclAT_2-Antitoxin
-2219530..2219630+101NuclAT_2-Antitoxin
-2219530..2219630+101NuclAT_2-Antitoxin
D3Z87_RS115452219964..2220575-612WP_009967516.1lipoprotein-
D3Z87_RS115502220690..2221016-327WP_009967517.1helix-turn-helix domain-containing protein-
D3Z87_RS115552221969..2222163+195WP_004399291.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
insideProphage--2151258..2286037134779


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-137)


Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6882.45 Da        Isoelectric Point: 12.8833

>T111625 WP_009967515.1 NZ_CP032310:c2219589-2219413 [Bacillus subtilis]
VLEKMGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Download         Length: 177 bp

>T111625 NZ_CP032310:c2219589-2219413 [Bacillus subtilis]
GTGCTTGAGAAAATGGGTATCGTAGTTGCTTTCCTCATATCTTTAACGGTTCTTACAATCAACAGTCTAACAATAGTTGA
GAAGGTAAGAAACCTAAAGAATGGGACAAGCAAAAAGAAAAAGCGTATACGCAAGCGGCTCCGACCAAAGAGACAACGCC
AACGTATACGCCGATGA

Antitoxin


Download         Length: 101 bp

>AT111625 NZ_CP032310:2219530-2219630 [Bacillus subtilis]
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTACGATACCCATTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBO31941

Antitoxin

Download structure file

References