Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) yonT-SR6/-
Location 2185329..2185658 Replicon chromosome
Accession NZ_AP024624
Organism Bacillus subtilis strain BEST3106

Toxin (Protein)


Gene name yonT Uniprot ID C0H439
Locus tag K6J91_RS11225 Protein ID WP_010886546.1
Coordinates 2185329..2185580 (-) Length 84 a.a.

Antitoxin (RNA)


Gene name SR6
Locus tag -
Coordinates 2185558..2185658 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6J91_RS11200 2180787..2181014 - 228 WP_004399298.1 helix-turn-helix transcriptional regulator -
K6J91_RS11205 2181275..2182591 - 1317 WP_004399369.1 hypothetical protein -
K6J91_RS11210 2182948..2183454 - 507 WP_004399486.1 hypothetical protein -
K6J91_RS11215 2183782..2185014 - 1233 WP_004399445.1 hypothetical protein -
K6J91_RS11220 2185096..2185284 - 189 WP_004399547.1 hypothetical protein -
K6J91_RS11225 2185329..2185580 - 252 WP_010886546.1 hypothetical protein Toxin
- 2185558..2185658 + 101 - - Antitoxin
K6J91_RS11230 2185599..2185775 - 177 WP_009967515.1 hypothetical protein -
- 2185716..2185816 + 101 NuclAT_2 - -
- 2185716..2185816 + 101 NuclAT_2 - -
- 2185716..2185816 + 101 NuclAT_2 - -
- 2185716..2185816 + 101 NuclAT_2 - -
K6J91_RS11235 2186150..2186761 - 612 WP_009967516.1 lipoprotein -
K6J91_RS11240 2186876..2187202 - 327 WP_009967517.1 helix-turn-helix transcriptional regulator -
K6J91_RS11245 2188155..2188349 + 195 WP_004399291.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2117443..2266470 149027


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9956.96 Da        Isoelectric Point: 9.7930

>T39035 WP_010886546.1 NZ_AP024624:c2185580-2185329 [Bacillus subtilis]
MNFSFSSYPYYNMIKHIANMKRFSLWFTHITFIGLFLMFQLIKDYFSSEGQALINTIFVVTCIIAILLWIIYCVFLKLRN
KSH

Download         Length: 252 bp

>T39035 NZ_AP024624:c2185580-2185329 [Bacillus subtilis]
ATGAACTTCTCCTTTAGTTCCTACCCATATTATAACATGATCAAGCACATTGCAAACATGAAACGATTCTCATTATGGTT
TACCCATATCACATTCATTGGCTTATTCTTAATGTTTCAACTCATCAAAGATTACTTCAGCAGCGAAGGACAGGCGCTAA
TCAACACAATTTTTGTTGTCACATGTATCATTGCCATATTGTTATGGATCATCTATTGTGTATTCCTTAAACTAAGAAAC
AAGTCACACTAA

Antitoxin


Download         Length: 101 bp

>AT39035 NZ_AP024624:2185558-2185658 [Bacillus subtilis]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCGGCGTATACGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB C0H439

Antitoxin

Download structure file

References