Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) bsrG-as-bsrH/-
Location 3901082..3901372 Replicon chromosome
Accession NZ_CP064095
Organism Bacillus subtilis strain N1303-2Ay

Toxin (Protein)


Gene name bsrG Uniprot ID L8EAY0
Locus tag IRJ27_RS20335 Protein ID WP_009967548.1
Coordinates 3901256..3901372 (-) Length 39 a.a.

Antitoxin (RNA)


Gene name as-bsrH
Locus tag -
Coordinates 3901082..3901261 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IRJ27_RS20305 (3896619) 3896619..3896753 - 135 WP_234047931.1 transposase -
IRJ27_RS20310 (3896888) 3896888..3897445 + 558 WP_003246042.1 SMI1/KNR4 family protein -
IRJ27_RS20315 (3897545) 3897545..3899260 + 1716 WP_004398855.1 ribonuclease YeeF family protein -
IRJ27_RS20320 (3899269) 3899269..3899766 + 498 WP_003246188.1 SMI1/KNR4 family protein -
IRJ27_RS20325 (3899830) 3899830..3900408 + 579 WP_004399123.1 SMI1/KNR4 family protein -
IRJ27_RS20330 (3900444) 3900444..3900977 + 534 WP_004399156.1 GNAT family protein -
- (3901082) 3901082..3901261 + 180 NuclAT_1 - Antitoxin
- (3901082) 3901082..3901261 + 180 NuclAT_1 - Antitoxin
- (3901082) 3901082..3901261 + 180 NuclAT_1 - Antitoxin
- (3901082) 3901082..3901261 + 180 NuclAT_1 - Antitoxin
IRJ27_RS20335 (3901256) 3901256..3901372 - 117 WP_009967548.1 type I toxin-antitoxin system toxin BsrG Toxin
IRJ27_RS20340 (3901603) 3901603..3902070 + 468 WP_003246138.1 YolA family protein -
IRJ27_RS20345 (3902076) 3902076..3902432 + 357 WP_004398595.1 hypothetical protein -
IRJ27_RS20350 (3902475) 3902475..3902810 - 336 WP_004399073.1 hypothetical protein -
IRJ27_RS20355 (3902984) 3902984..3903316 + 333 WP_004398710.1 YolD-like family protein -
IRJ27_RS20360 (3903309) 3903309..3904559 + 1251 WP_004398504.1 UV-damage repair protein uvrX -
IRJ27_RS20365 (3904661) 3904661..3904978 + 318 WP_009967545.1 sublancin immunity protein SunI -
IRJ27_RS20370 (3905275) 3905275..3905445 + 171 WP_009967544.1 bacteriocin sublancin-168 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 3874311..4023340 149029


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(1-38)


Sequences

Toxin        


Download         Length: 39 a.a.        Molecular weight: 4336.39 Da        Isoelectric Point: 10.1022

>T180082 WP_009967548.1 NZ_CP064095:c3901372-3901256 [Bacillus subtilis]
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK

Download         Length: 117 bp

>T180082 NZ_CP085063:313058-313161 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 180 bp

>AT180082 NZ_CP064095:3901082-3901261 [Bacillus subtilis]
AATGATACAATTATATAATTATTTTTTGCATTTTGTTTAATTAAATGCATAAAATAAAAAGACCAGGGTGTTGGTAGCAC
CCTGGCTCTGTACAAAAGCTGCCCATCAAAGGGCTTGCTCGTTGTCAAATCTGCGTAGGCCTAACCCTTCAGGTGTCCAA
ACTCAAGGGAAGGTCTATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7Z7EVU9

Antitoxin

Download structure file

References