Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) yonT-as-bsrG/-
Location 2188384..2188601 Replicon chromosome
Accession NZ_AP024623
Organism Bacillus subtilis strain BEST3102

Toxin (Protein)


Gene name yonT Uniprot ID O31941
Locus tag K6J99_RS11220 Protein ID WP_009967515.1
Coordinates 2188384..2188560 (-) Length 59 a.a.

Antitoxin (RNA)


Gene name as-bsrG
Locus tag -
Coordinates 2188501..2188601 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6J99_RS11190 (2183572) 2183572..2183799 - 228 WP_004399298.1 helix-turn-helix transcriptional regulator -
K6J99_RS11195 (2184060) 2184060..2185376 - 1317 WP_004399369.1 hypothetical protein -
K6J99_RS11200 (2185733) 2185733..2186239 - 507 WP_004399486.1 hypothetical protein -
K6J99_RS11205 (2186567) 2186567..2187799 - 1233 WP_004399445.1 hypothetical protein -
K6J99_RS11210 (2187881) 2187881..2188069 - 189 WP_004399547.1 hypothetical protein -
K6J99_RS11215 (2188114) 2188114..2188365 - 252 WP_010886546.1 hypothetical protein -
K6J99_RS11220 (2188384) 2188384..2188560 - 177 WP_009967515.1 hypothetical protein Toxin
- (2188501) 2188501..2188601 + 101 NuclAT_2 - Antitoxin
- (2188501) 2188501..2188601 + 101 NuclAT_2 - Antitoxin
- (2188501) 2188501..2188601 + 101 NuclAT_2 - Antitoxin
- (2188501) 2188501..2188601 + 101 NuclAT_2 - Antitoxin
K6J99_RS11225 (2188935) 2188935..2189546 - 612 WP_009967516.1 lipoprotein -
K6J99_RS11230 (2189661) 2189661..2189987 - 327 WP_009967517.1 helix-turn-helix transcriptional regulator -
K6J99_RS11235 (2190940) 2190940..2191134 + 195 WP_004399291.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2120228..2255008 134780


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6882.45 Da        Isoelectric Point: 12.8833

>T39018 WP_009967515.1 NZ_AP024623:c2188560-2188384 [Bacillus subtilis]
VLEKMGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Download         Length: 177 bp

>T39018 NZ_AP024623:c2188560-2188384 [Bacillus subtilis]
GTGCTTGAGAAAATGGGTATCGTAGTTGCTTTCCTCATATCTTTAACGGTTCTTACAATCAACAGTCTAACAATAGTTGA
GAAGGTAAGAAACCTAAAGAATGGGACAAGCAAAAAGAAAAAGCGTATACGCAAGCGGCTCCGACCAAAGAGACAACGCC
AACGTATACGCCGATGA

Antitoxin


Download         Length: 101 bp

>AT39018 NZ_AP024623:2188501-2188601 [Bacillus subtilis]
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTACGATACCCATTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB O31941

Antitoxin

Download structure file

References