38999

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) bsrG-as-bsrH/-
Location 2252762..2253052 Replicon chromosome
Accession NZ_AP024622
Organism Bacillus subtilis strain BEST3096

Toxin (Protein)


Gene name bsrG Uniprot ID L8EAY0
Locus tag K6K01_RS11565 Protein ID WP_009967548.1
Coordinates 2252762..2252878 (+) Length 39 a.a.

Antitoxin (RNA)


Gene name as-bsrH
Locus tag -
Coordinates 2252873..2253052 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6K01_RS11530 (2248689) 2248689..2248859 - 171 WP_009967544.1 bacteriocin sublancin-168 -
K6K01_RS11535 (2249156) 2249156..2249473 - 318 WP_009967545.1 sublancin immunity protein SunI -
K6K01_RS11540 (2249575) 2249575..2250825 - 1251 WP_004398504.1 UV-damage repair protein uvrX -
K6K01_RS11545 (2250818) 2250818..2251150 - 333 WP_004398710.1 YolD-like family protein -
K6K01_RS11550 (2251324) 2251324..2251659 + 336 WP_004399073.1 hypothetical protein -
K6K01_RS11555 (2251702) 2251702..2252058 - 357 WP_004398595.1 hypothetical protein -
K6K01_RS11560 (2252064) 2252064..2252531 - 468 WP_003246138.1 YolA family protein -
K6K01_RS11565 (2252762) 2252762..2252878 + 117 WP_009967548.1 type I toxin-antitoxin system toxin BsrG Toxin
- (2252873) 2252873..2253052 - 180 NuclAT_1 - Antitoxin
- (2252873) 2252873..2253052 - 180 NuclAT_1 - Antitoxin
- (2252873) 2252873..2253052 - 180 NuclAT_1 - Antitoxin
- (2252873) 2252873..2253052 - 180 NuclAT_1 - Antitoxin
K6K01_RS11570 (2253157) 2253157..2253690 - 534 WP_004399156.1 GNAT family protein -
K6K01_RS11575 (2253726) 2253726..2254304 - 579 WP_004399123.1 SMI1/KNR4 family protein -
K6K01_RS11580 (2254368) 2254368..2254865 - 498 WP_003246188.1 SMI1/KNR4 family protein -
K6K01_RS11585 (2254874) 2254874..2256589 - 1716 WP_004398855.1 ribonuclease YeeF family protein -
K6K01_RS11590 (2256689) 2256689..2257246 - 558 WP_003246042.1 SMI1/KNR4 family protein -
K6K01_RS11595 (2257381) 2257381..2257515 + 135 WP_234047931.1 transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2130796..2265576 134780


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(1-38)


Sequences

Toxin        


Download         Length: 39 a.a.        Molecular weight: 4336.39 Da        Isoelectric Point: 10.1022

>T38999 WP_009967548.1 NZ_AP024622:2252762-2252878 [Bacillus subtilis]
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK

Download         Length: 117 bp

>T38999 NZ_AP024622:2252762-2252878 [Bacillus subtilis]
ATGACTGTTTACGAATCATTAATGATAATGATCAATTTTGGCGGATTGATATTAAATACCGTCTTGTTGATCTTCAATAT
AATGATGATTGTAACGTCAAGCCAAAAGAAAAAATAG

Antitoxin


Download         Length: 180 bp

>AT38999 NZ_AP024622:c2253052-2252873 [Bacillus subtilis]
AATGATACAATTATATAATTATTTTTTGCATTTTGTTTAATTAAATGCATAAAATAAAAAGACCAGGGTGTTGGTAGCAC
CCTGGCTCTGTACAAAAGCTGCCCATCAAAGGGCTTGCTCGTTGTCAAATCTGCGTAGGCCTAACCCTTCAGGTGTCCAA
ACTCAAGGGAAGGTCTATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7Z7EVU9

Antitoxin

Download structure file

References