Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) yonT-SR6/-
Location 2198911..2199128 Replicon chromosome
Accession NZ_AP024622
Organism Bacillus subtilis strain BEST3096

Toxin (Protein)


Gene name yonT Uniprot ID O31941
Locus tag K6K01_RS11270 Protein ID WP_009967515.1
Coordinates 2198952..2199128 (-) Length 59 a.a.

Antitoxin (RNA)


Gene name SR6
Locus tag -
Coordinates 2198911..2199011 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6K01_RS11240 2194140..2194367 - 228 WP_004399298.1 helix-turn-helix transcriptional regulator -
K6K01_RS11245 2194628..2195944 - 1317 WP_004399369.1 hypothetical protein -
K6K01_RS11250 2196301..2196807 - 507 WP_004399486.1 hypothetical protein -
K6K01_RS11255 2197135..2198367 - 1233 WP_004399445.1 hypothetical protein -
K6K01_RS11260 2198449..2198637 - 189 WP_004399547.1 hypothetical protein -
K6K01_RS11265 2198682..2198933 - 252 WP_010886546.1 hypothetical protein -
- 2198911..2199011 + 101 - - Antitoxin
K6K01_RS11270 2198952..2199128 - 177 WP_009967515.1 hypothetical protein Toxin
- 2199069..2199169 + 101 NuclAT_2 - -
- 2199069..2199169 + 101 NuclAT_2 - -
- 2199069..2199169 + 101 NuclAT_2 - -
- 2199069..2199169 + 101 NuclAT_2 - -
K6K01_RS11275 2199503..2200114 - 612 WP_009967516.1 lipoprotein -
K6K01_RS11280 2200229..2200555 - 327 WP_009967517.1 helix-turn-helix transcriptional regulator -
K6K01_RS11285 2201508..2201702 + 195 WP_004399291.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2130796..2265576 134780


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6882.45 Da        Isoelectric Point: 12.8833

>T38992 WP_009967515.1 NZ_AP024622:c2199128-2198952 [Bacillus subtilis]
VLEKMGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Download         Length: 177 bp

>T38992 NZ_AP024622:c2199128-2198952 [Bacillus subtilis]
GTGCTTGAGAAAATGGGTATCGTAGTTGCTTTCCTCATATCTTTAACGGTTCTTACAATCAACAGTCTAACAATAGTTGA
GAAGGTAAGAAACCTAAAGAATGGGACAAGCAAAAAGAAAAAGCGTATACGCAAGCGGCTCCGACCAAAGAGACAACGCC
AACGTATACGCCGATGA

Antitoxin


Download         Length: 101 bp

>AT38992 NZ_AP024622:2198911-2199011 [Bacillus subtilis]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCGGCGTATACGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB O31941

Antitoxin

Download structure file

References