Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) yonT-as-bsrG/-
Location 3466108..3466325 Replicon chromosome
Accession NZ_CP064094
Organism Bacillus subtilis strain N1108-5at

Toxin (Protein)


Gene name yonT Uniprot ID O31941
Locus tag IRJ26_RS18440 Protein ID WP_009967515.1
Coordinates 3466149..3466325 (+) Length 59 a.a.

Antitoxin (RNA)


Gene name as-bsrG
Locus tag -
Coordinates 3466108..3466208 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IRJ26_RS18425 (3463575) 3463575..3463769 - 195 WP_004399291.1 hypothetical protein -
IRJ26_RS18430 (3464722) 3464722..3465048 + 327 WP_009967517.1 helix-turn-helix transcriptional regulator -
IRJ26_RS18435 (3465163) 3465163..3465774 + 612 WP_009967516.1 lipoprotein -
- (3466108) 3466108..3466208 - 101 NuclAT_2 - Antitoxin
- (3466108) 3466108..3466208 - 101 NuclAT_2 - Antitoxin
- (3466108) 3466108..3466208 - 101 NuclAT_2 - Antitoxin
- (3466108) 3466108..3466208 - 101 NuclAT_2 - Antitoxin
IRJ26_RS18440 (3466149) 3466149..3466325 + 177 WP_009967515.1 hypothetical protein Toxin
IRJ26_RS18445 (3466344) 3466344..3466595 + 252 WP_010886546.1 hypothetical protein -
IRJ26_RS18450 (3466640) 3466640..3466828 + 189 WP_004399547.1 hypothetical protein -
IRJ26_RS18455 (3466910) 3466910..3468142 + 1233 WP_004399445.1 hypothetical protein -
IRJ26_RS18460 (3468470) 3468470..3468976 + 507 WP_004399486.1 hypothetical protein -
IRJ26_RS18465 (3469333) 3469333..3470649 + 1317 WP_004399369.1 hypothetical protein -
IRJ26_RS18470 (3470910) 3470910..3471137 + 228 WP_004399298.1 helix-turn-helix transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 3385454..3534483 149029


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6882.45 Da        Isoelectric Point: 12.8833

>T180063 WP_009967515.1 NZ_CP064094:3466149-3466325 [Bacillus subtilis]
VLEKMGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Download         Length: 177 bp

>T180063 NZ_CP085060:c1993370-1993263 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 101 bp

>AT180063 NZ_CP064094:c3466208-3466108 [Bacillus subtilis]
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTACGATACCCATTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB O31941

Antitoxin

Download structure file

References