Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) yonT-SR6/-
Location 2268276..2268493 Replicon chromosome
Accession NZ_OX419580
Organism Bacillus subtilis isolate NRS6116

Toxin (Protein)


Gene name yonT Uniprot ID O31941
Locus tag KJP60_RS11815 Protein ID WP_009967515.1
Coordinates 2268317..2268493 (-) Length 59 a.a.

Antitoxin (RNA)


Gene name SR6
Locus tag -
Coordinates 2268276..2268376 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KJP60_RS11785 2263505..2263732 - 228 WP_004399298.1 helix-turn-helix transcriptional regulator -
KJP60_RS11790 2263993..2265309 - 1317 Protein_2274 hypothetical protein -
KJP60_RS11795 2265666..2266172 - 507 WP_004399486.1 hypothetical protein -
KJP60_RS11800 2266500..2267732 - 1233 WP_004399445.1 hypothetical protein -
KJP60_RS11805 2267814..2268002 - 189 WP_004399547.1 hypothetical protein -
KJP60_RS11810 2268047..2268298 - 252 WP_010886546.1 hypothetical protein -
- 2268276..2268376 + 101 - - Antitoxin
KJP60_RS11815 2268317..2268493 - 177 WP_009967515.1 hypothetical protein Toxin
- 2268434..2268534 + 101 NuclAT_2 - -
- 2268434..2268534 + 101 NuclAT_2 - -
- 2268434..2268534 + 101 NuclAT_2 - -
- 2268434..2268534 + 101 NuclAT_2 - -
KJP60_RS11820 2268868..2269479 - 612 WP_009967516.1 lipoprotein -
KJP60_RS11825 2269594..2269920 - 327 WP_009967517.1 helix-turn-helix transcriptional regulator -
KJP60_RS11830 2270873..2271067 + 195 WP_004399291.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2200159..2334941 134782


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6882.45 Da        Isoelectric Point: 12.8833

>T296935 WP_009967515.1 NZ_OX419580:c2268493-2268317 [Bacillus subtilis]
VLEKMGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Download         Length: 177 bp

Antitoxin


Download         Length: 101 bp

>AT296935 NZ_OX419580:2268276-2268376 [Bacillus subtilis]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCGGCGTATACGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB O31941

Antitoxin

Download structure file

References