53442

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) bsrG-as-bsrH/-
Location 2273600..2273890 Replicon chromosome
Accession NZ_CP011115
Organism Bacillus subtilis KCTC 1028 = ATCC 6051a strain KCTC 1028

Toxin (Protein)


Gene name bsrG Uniprot ID L8EAY0
Locus tag O7A_RS23415 Protein ID WP_009967548.1
Coordinates 2273600..2273716 (+) Length 39 a.a.

Antitoxin (RNA)


Gene name as-bsrH
Locus tag -
Coordinates 2273711..2273890 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O7A_RS11785 2269527..2269697 - 171 WP_009967544.1 bacteriocin sublancin-168 -
O7A_RS11790 2269994..2270311 - 318 WP_009967545.1 sublancin immunity protein SunI -
O7A_RS11795 2270413..2271663 - 1251 WP_004398504.1 UV-damage repair protein uvrX -
O7A_RS11800 2271656..2271988 - 333 WP_004398710.1 YolD-like family protein -
O7A_RS11805 2272162..2272497 + 336 WP_004399073.1 hypothetical protein -
O7A_RS11810 2272540..2272896 - 357 WP_004398595.1 hypothetical protein -
O7A_RS11815 2272902..2273369 - 468 WP_003246138.1 YolA family protein -
O7A_RS23415 2273600..2273716 + 117 WP_009967548.1 type I toxin-antitoxin system toxin BsrG Toxin
- 2273711..2273890 - 180 NuclAT_1 - Antitoxin
- 2273711..2273890 - 180 NuclAT_1 - Antitoxin
- 2273711..2273890 - 180 NuclAT_1 - Antitoxin
- 2273711..2273890 - 180 NuclAT_1 - Antitoxin
O7A_RS11825 2273995..2274528 - 534 WP_004399156.1 GNAT family N-acetyltransferase -
O7A_RS11830 2274564..2275142 - 579 WP_004399123.1 SMI1/KNR4 family protein -
O7A_RS11835 2275206..2275703 - 498 WP_003246188.1 SMI1/KNR4 family protein -
O7A_RS11840 2275712..2277427 - 1716 WP_004398855.1 ribonuclease YeeF family protein -
O7A_RS11845 2277527..2278084 - 558 WP_003246042.1 SMI1/KNR4 family protein -
O7A_RS22765 2278168..2278353 + 186 WP_003245951.1 transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2151632..2286414 134782


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(1-38)


Sequences

Toxin        


Download         Length: 39 a.a.        Molecular weight: 4336.39 Da        Isoelectric Point: 10.1022

>T53442 WP_009967548.1 NZ_CP011115:2273600-2273716 [Bacillus subtilis KCTC 1028 = ATCC 6051a]
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK

Download         Length: 117 bp

>T53442 NZ_CP011115:2273600-2273716 [Bacillus subtilis KCTC 1028 = ATCC 6051a]
ATGACTGTTTACGAATCATTAATGATAATGATCAATTTTGGCGGATTGATATTAAATACCGTCTTGTTGATCTTCAATAT
AATGATGATTGTAACGTCAAGCCAAAAGAAAAAATAG

Antitoxin


Download         Length: 180 bp

>AT53442 NZ_CP011115:c2273890-2273711 [Bacillus subtilis KCTC 1028 = ATCC 6051a]
AATGATACAATTATATAATTATTTTTTGCATTTTGTTTAATTAAATGCATAAAATAAAAAGACCAGGGTGTTGGTAGCAC
CCTGGCTCTGTACAAAAGCTGCCCATCAAAGGGCTTGCTCGTTGTCAAATCTGCGTAGGCCTAACCCTTCAGGTGTCCAA
ACTCAAGGGAAGGTCTATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7Z7EVU9

Antitoxin

Download structure file

References