Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) yonT-SR6/-
Location 2265064..2265281 Replicon chromosome
Accession NZ_OX419569
Organism Bacillus subtilis isolate NRS6118

Toxin (Protein)


Gene name yonT Uniprot ID O31941
Locus tag KJP55_RS11715 Protein ID WP_009967515.1
Coordinates 2265105..2265281 (-) Length 59 a.a.

Antitoxin (RNA)


Gene name SR6
Locus tag -
Coordinates 2265064..2265164 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KJP55_RS11685 2260293..2260520 - 228 WP_004399298.1 helix-turn-helix transcriptional regulator -
KJP55_RS11690 2260781..2262097 - 1317 WP_004399369.1 hypothetical protein -
KJP55_RS11695 2262454..2262960 - 507 WP_004399486.1 hypothetical protein -
KJP55_RS11700 2263288..2264520 - 1233 WP_004399445.1 hypothetical protein -
KJP55_RS11705 2264602..2264790 - 189 WP_004399547.1 hypothetical protein -
KJP55_RS11710 2264835..2265086 - 252 WP_010886546.1 hypothetical protein -
- 2265064..2265164 + 101 - - Antitoxin
KJP55_RS11715 2265105..2265281 - 177 WP_009967515.1 hypothetical protein Toxin
- 2265222..2265322 + 101 NuclAT_2 - -
- 2265222..2265322 + 101 NuclAT_2 - -
- 2265222..2265322 + 101 NuclAT_2 - -
- 2265222..2265322 + 101 NuclAT_2 - -
KJP55_RS11720 2265656..2266267 - 612 WP_009967516.1 lipoprotein -
KJP55_RS11725 2266382..2266708 - 327 WP_009967517.1 helix-turn-helix transcriptional regulator -
KJP55_RS11730 2267661..2267855 + 195 WP_004399291.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2195159..2345976 150817


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 59 a.a.        Molecular weight: 6882.45 Da        Isoelectric Point: 12.8833

>T296851 WP_009967515.1 NZ_OX419569:c2265281-2265105 [Bacillus subtilis]
VLEKMGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Download         Length: 177 bp


Antitoxin


Download         Length: 101 bp

>AT296851 NZ_OX419569:2265064-2265164 [Bacillus subtilis]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCGGCGTATACGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB O31941


Antitoxin

Download structure file

References