20384

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1856535..1856715 Replicon chromosome
Accession NC_002745
Organism Staphylococcus aureus subsp. aureus N315

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag SA_RS15155 Protein ID WP_001801861.1
Coordinates 1856535..1856630 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1856658..1856715 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SA_RS09095 (SA1617) 1851698..1852348 + 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -
SA_RS09100 (SA1618) 1852429..1853424 + 996 WP_000070642.1 DUF4352 domain-containing protein -
SA_RS09105 (SA1619) 1853499..1854125 + 627 WP_000669024.1 hypothetical protein -
SA_RS09110 (SA1620) 1854166..1854507 + 342 WP_000627540.1 DUF3969 family protein -
SA_RS09115 (SA1621) 1854608..1855180 + 573 WP_000414216.1 hypothetical protein -
SA_RS14770 1855378..1856390 - 1013 Protein_1723 IS3 family transposase -
SA_RS15155 1856535..1856630 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1856658..1856715 - 58 - - Antitoxin
SA_RS09135 1856753..1856854 + 102 WP_001792025.1 hypothetical protein -
SA_RS15160 1856832..1856993 - 162 Protein_1726 transposase -
SA_RS09140 (SA1624) 1856984..1857478 - 495 Protein_1727 transposase -
SA_RS09145 (SA1625) 1857930..1859159 - 1230 WP_000072627.1 restriction endonuclease subunit S -
SA_RS09150 (SA1626) 1859152..1860708 - 1557 WP_000028669.1 type I restriction-modification system subunit M -
SA_RS09155 1860872..1861006 - 135 WP_001791797.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA / selk 1850940..1883547 32607


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T20384 WP_001801861.1 NC_002745:1856535-1856630 [Staphylococcus aureus subsp. aureus N315]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T20384 NC_002745:1856535-1856630 [Staphylococcus aureus subsp. aureus N315]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT20384 NC_002745:c1856715-1856658 [Staphylococcus aureus subsp. aureus N315]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References