Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1978900..1979080 Replicon chromosome
Accession NZ_CP030326
Organism Staphylococcus aureus strain AR_474

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag CSC59_RS10325 Protein ID WP_001801861.1
Coordinates 1978900..1978995 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1979023..1979080 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CSC59_RS10295 1974063..1974713 + 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -
CSC59_RS10300 1974794..1975789 + 996 WP_000070642.1 DUF4352 domain-containing protein -
CSC59_RS10305 1975864..1976490 + 627 WP_000669024.1 hypothetical protein -
CSC59_RS10310 1976531..1976872 + 342 WP_000627540.1 DUF3969 family protein -
CSC59_RS10315 1976973..1977545 + 573 WP_000414216.1 hypothetical protein -
CSC59_RS10320 1977743..1978755 - 1013 Protein_1909 IS3 family transposase -
CSC59_RS10325 1978900..1978995 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1979023..1979080 - 58 - - Antitoxin
CSC59_RS10330 1979118..1979219 + 102 WP_001792025.1 hypothetical protein -
CSC59_RS10335 1979197..1979358 - 162 Protein_1912 transposase -
CSC59_RS10340 1979349..1979843 - 495 Protein_1913 transposase -
CSC59_RS10345 1980295..1981524 - 1230 WP_000072627.1 restriction endonuclease subunit S -
CSC59_RS10350 1981517..1983073 - 1557 WP_000028669.1 type I restriction-modification system subunit M -
CSC59_RS10355 1983237..1983371 - 135 WP_001791797.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA / selk 1973304..2005036 31732


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T107693 WP_001801861.1 NZ_CP030326:1978900-1978995 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T107693 NZ_CP030326:1978900-1978995 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT107693 NZ_CP030326:c1979080-1979023 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References